Evidence map›Paper›PMID 42409923›Full record

ArticleBritish journal of cancer2026

Oligometastatic neuroendocrine tumors: characteristics and prognosis.

Philipp Melhorn, Julia Postmann, Markus Raderer, Barbara Kiesewetter

Abstract read
In one paragraph

Article in British journal of cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Philipp MelhornDivision of Oncology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.ORCID http://orcid.org/0000-0002-8920-0206
Julia PostmannDivision of Oncology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
Markus RadererDivision of Oncology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
Barbara KiesewetterDivision of Oncology, Department of Medicine I, Medical University of Vienna, Vienna, Austria. barbara.kiesewetter@meduniwien.ac.at.ORCID http://orcid.org/0000-0002-5490-2371

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOligometastatic disease (OMD) in neuroendocrine tumors (NET) has hardly been investigated so far and it is unclear how OMD should influence treatment decisions.

methodsThe primary objective of this retrospective analysis was to evaluate characteristics and prognosis of the OMD state in patients with NET G1/G2 of gastroenteropancreatic origin.

resultsThe overall study cohort comprised 190 patients. OMD occurred in 29% of patients (n = 55), 58% of those (n = 32) had synchronous oligometastases. Oligometastases were limited to one organ in most patients (95%) and primarily involved the liver (83% or n = 43/52). Median overall survival (OS) from diagnosis was 117.5 months (95% CI 102.4-149.1 months). Calculated from first metastasis, median OS was 102.4 months (95% CI 98.3-117.5 months) and not significantly longer in oligometastatic patients (117.5 months) versus polymetastatic patients (100.2 months). Locoregional treatment of oligometastases was performed in 24/55 patients (44%) and showed a non-significant trend towards superior survival compared to no such treatment (125.4 versus 99.7 months).

conclusionsThese results suggest that a low absolute number of metastases alone may not be a clear prognostic factor in NET. It remains unknown if locoregional therapies can achieve long-term disease-free survival in a significant number of oligometastatic NET patients.

Indexed as

Intestinal NeoplasmsLiver NeoplasmsNeuroendocrine TumorsPancreatic NeoplasmsAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedNeoplasm MetastasisPrognosisRetrospective Studies

Identifiers

PMID42409923
PMCPMC13578218

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