Evidence map›Paper›PMID 42409758›Full record

Trial reportJournal of oral rehabilitation2026

The Dynamics of Pharyngeal Shortening in Healthy Swallowing: Effects of Sex, Age, Bolus Volume and Consistency.

Dominie Yu, Renata Mancopes, Hilary Milne, Melanie Peladeau-Pigeon, Keara Boyce, Harmonie Chan, Maureen Folsom, Sophia Werden Abrams, Ashwini M Namasivayam-MacDonald, Emily K Plowman and 1 more

Registry-linked trialAbstract readClinical TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of oral rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05497219 (Establishing Reference Values and Clinical Decision Points for Quantitative Videofluoroscopic Measures of Swallowing), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05497219 naenrolling by invitationnot on this map

Establishing Reference Values and Clinical Decision Points for Quantitative Videofluoroscopic Measures of Swallowing

TypeinterventionalSponsorUniversity Health Network, TorontoRan2022 to 2027Enrolled580ConditionsDysphagia, OropharyngealArmsVideofluoroscopic Swallowing Study (VF)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dominie YuKITE Research Institute, University Health Network, Toronto, Ontario, Canada.
Renata MancopesKITE Research Institute, University Health Network, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-9941-7508
Hilary MilneKITE Research Institute, University Health Network, Toronto, Ontario, Canada.
Melanie Peladeau-PigeonKITE Research Institute, University Health Network, Toronto, Ontario, Canada.
Keara BoyceSchool of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada.
Harmonie ChanSchool of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada.
Maureen FolsomAerodigestive Research Core, The Ohio State University, Columbus, Ohio, USA.
Sophia Werden AbramsSchool of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada.
Ashwini M Namasivayam-MacDonaldSchool of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada.ORCID https://orcid.org/0000-0002-9473-8844
Emily K PlowmanAerodigestive Research Core, The Ohio State University, Columbus, Ohio, USA.
Catriona M SteeleKITE Research Institute, University Health Network, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-4294-6561

Funding

Establishing Reference Values and Clinical Decision Points for Quantitative Videofluoroscopic Measures of SwallowingR01AG077481 · NIA · UNIVERSITY HEALTH NETWORK · PI Emily Kate Plowman, Catriona Margaret Steele · 2022 to 2026
$4.3M
NIA NIH HHS R01 AG077481NIA NIH HHS R01AG077481
6 · The paper itself

Abstract

backgroundPharyngeal shortening is thought to facilitate bolus clearance through the pharynx and upper oesophageal sphincter (UES) in swallowing. However, little information is available regarding pharyngeal shortening in healthy swallowing. OBJECTIVE(S): We characterised the timing and extent of pharyngeal shortening by tracking the height of the UES across key time points in healthy swallowing. Additionally, we identified variations in pharyngeal shortening attributable to participant (sex, age) and bolus factors (consistency, volume).

methodsVideofluoroscopy data for (1) sips of thin liquid and (2) teaspoons of mildly thick liquid were analysed from 80 healthy adults (40 males, 40 females), distributed across four age groups: 18-35, 36-53, 54-72, 73-90 years. UES height was tracked relative to the cervical spine on the frames of UES opening (UESO), maximum UES height (UESMaxHeight) and swallow rest (SR) using a 20-point ordinal scale. Statistical analyses explored effects of sex, age-group, and task on: (1) latency-to-UESMaxHeight, (2) UES height at UESO and SR, and (3) the degree of pharyngeal shortening at UESMaxHeight relative to UESO and SR.

resultsMaximum UES height occurred between the events of UES opening and closure, in close proximity to other biomechanically linked events. UES height was lower in males. Greater pharyngeal shortening was seen in males and on thin liquid tasks.

conclusionThese findings refine our understanding of healthy swallowing dynamics and highlight the influence of sex-linked differences in height on UES position relative to the cervical spine.

trial registrationClinicalTrials.gov: NCT05497219.

Indexed as

DeglutitionEsophageal Sphincter, UpperPharynxAdolescentAdultAgedAged, 80 and overAge FactorsFemaleFluoroscopyHumansMaleMiddle AgedSex FactorsYoung Adultdeglutitionpharynxvideofluoroscopy

Identifiers

PMID42409758
PMCPMC13653302

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