Evidence map›Paper›PMID 42409422›Full record

ArticleBMJ open quality2026

Improving compliance with curative radiotherapy for cervical cancer in a high-volume centre in India: a bundled workflow (AID-CARE) quality improvement project.

Sreenivasa Rao Bonala, Bala Venkata Subramanian, Cherwin Venati, Henita Selvamary, Naveen Bhargav Talatoti, Gongada Sindhu

Abstract read
In one paragraph

Article in BMJ open quality, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Sreenivasa Rao BonalaRadiation Oncology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India doctorrt12@gmail.com.ORCID 0009-0000-1961-844X
Bala Venkata SubramanianRadiation Oncology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.
Cherwin VenatiRadiation Oncology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.ORCID 0000-0002-7062-0534
Henita SelvamaryRadiation Oncology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.ORCID 0000-0001-8499-3908
Naveen Bhargav TalatotiRadiation Oncology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.ORCID 0009-0003-1783-8838
Gongada SindhuRadiation Oncology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Timely completion of curative chemoradiotherapy within 56 days is a key determinant of oncological outcomes in cervical cancer; however, achieving this target remains challenging in high-volume public-sector settings in low- and middle-income countries (LMICs). At a tertiary public-sector cancer centre in South India, routine clinical observations identified poor compliance with recommended radiotherapy timelines, with delays and treatment defaults occurring at multiple points along the care pathway. In response, a quality improvement project was undertaken to improve treatment timeliness and completion.A retrospective baseline audit confirmed substantial delays and high default rates among patients receiving curative-intent external beam radiotherapy, followed by intracavitary brachytherapy. Root cause analysis identified system-, staff- and patient-related factors contributing to poor compliance. Based on these findings, a bundled workflow intervention (AID-CARE) was developed, incorporating early brachytherapy assessment, planned interdigitation, accelerated schedules for delayed cases, structured patient counselling, staff education and prospective patient tracking. The intervention was implemented using sequential Plan-Do-Study-Act cycles, followed by a prospective re-audit and sustainment phase. The primary outcomes were compliance with an overall treatment time of ≤56 days and treatment default rates assessed over time using run charts.At baseline, only 18.6% of patients completed treatment within 56 days, whereas 46.2% defaulted and 35.2% experienced prolonged treatment duration. Following implementation, compliance with the recommended treatment timeline improved to 70.1%, with a marked reduction in treatment defaults to 6.2%. These improvements were maintained during the sustainment phase. No increase in acute treatment-related toxicity was noted.This quality improvement initiative demonstrates that a structured, workflow-driven and resource-conscious approach can substantially and sustainably improve compliance with recommended radiotherapy timelines for cervical cancer in high-volume public-sector settings, with potential applicability to similar centres in LMICs.

Indexed as

RadiotherapyUterine Cervical NeoplasmsWorkflowAdherence InterventionsBrachytherapyFemaleHumansIndiaMiddle AgedProspective StudiesQuality ImprovementRetrospective StudiesTreatment DelayComplianceInterruptionsQuality improvementRadiotherapy

Identifiers

PMID42409422
PMCPMC13343099

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.