Evidence map›Paper›PMID 42407252›Full record

ArticleJournal of veterinary internal medicine2026

Testicular seminoma: clinical, imaging, and histologic features in nine horses.

Bridget Ratliff, Isabelle Kilcoyne, Pouya Dini, Scott A Katzman, Mitja Miklavcic, Melissa Chromik, Eunju Choi, Betsy Vaughan

Abstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Testicular Disorders in Equids: A Case Series.Animals : an open access journal from MDPI · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bridget RatliffComstock Equine Hospital, Reno, NV, United States.ORCID 0000-0001-8300-6245
Isabelle KilcoyneDepartment of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, CA, United States.ORCID 0000-0003-1147-6824
Pouya DiniDepartment of Population Health and Reproduction, School of Veterinary Medicine, University of California-Davis, Davis, CA, United States.ORCID 0000-0001-5553-5967
Scott A KatzmanDepartment of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, CA, United States.
Mitja MiklavcicDepartment of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, CA, United States.ORCID 0000-0001-8630-9452
Melissa ChromikDepartment of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California-Davis, Davis, CA, United States.
Eunju ChoiDepartment of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California-Davis, Davis, CA, United States.
Betsy VaughanDepartment of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, CA, United States.ORCID 0009-0004-8820-7192

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTesticular seminomas in horses are infrequently reported in the veterinary literature and long-term survival and metastatic potential are not well documented. HYPOTHESIS/

objectivesDescribe the clinical, imaging, and histologic features in 9 horses with testicular seminoma. ANIMALS: Medical records of 9 horses diagnosed with testicular seminoma at a referral hospital between 2000 and 2024 were reviewed.

methodsHorses were included if seminoma was confirmed on histopathology from biopsy or necropsy. Information retrieved included signalment, history, clinical pathology, ultrasonographic findings, treatment, and outcome.

resultsMedian age was 18 years (range, 8-26). Three of 9 horses presented for systemic disease (colic, 2; ventral edema, 1). All 3 had large abdominal masses palpable on rectal examination and were euthanized after diagnostic evaluation. Six horses presented for unilateral testicular enlargement (5) or cryptorchid castration (1). These horses underwent castration and the removed testes had features of malignancy with lymphatic neoplastic emboli. Five of 6 horses were euthanized between 4 months and 3 years after castration because of acute weight loss and abdominal masses identified on rectal examination or ultrasonographic examination, attributable to metastatic spread. One additional horse was euthanized for unrelated reasons. CONCLUSIONS AND CLINICAL IMPORTANCE: Horses presented with testicular enlargement and diagnosis of testicular seminoma should undergo diagnostic screening, including transabdominal or transrectal ultrasonographic examination to determine the presence of possible metastasis. Negative screening results at the time of diagnosis do not rule out the possibility of metastasis, and frequent screening at regular intervals is prudent in such cases. Horses with testicular seminoma of retained or descended testicles have a poor long term prognosis because of high potential for metastatic spread.

Indexed as

Horse DiseasesSeminomaTesticular NeoplasmsAnimalsHorsesMaleOrchiectomyRetrospective StudiesUltrasonographycryptorchidhorseseminomatesticleweight loss

Identifiers

PMID42407252
PMCPMC13336631

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.