Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
11 authors.
Rebeca Carballar-Lejarazú *Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025.ORCID 0000-0002-9338-8774
Yuemei Dong *W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Malaria Research Institute, Johns Hopkins University, Baltimore, MD 21205.ORCID 0000-0002-7902-2899
Thai Binh Pham *Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025.
Taylor Tushar *Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025.ORCID 0000-0001-6982-3249
Drusilla StillingerDepartment of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025.ORCID 0009-0000-2096-2520
Devin Ngoc NguyenDepartment of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025.ORCID 0009-0001-7860-0140
Lorena WinokurDepartment of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025.ORCID 0009-0005-0647-4439
Mihra TavadiaW. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Malaria Research Institute, Johns Hopkins University, Baltimore, MD 21205.ORCID 0000-0002-5335-9581
Mabel TaoW. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Malaria Research Institute, Johns Hopkins University, Baltimore, MD 21205.
George DimopoulosW. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Malaria Research Institute, Johns Hopkins University, Baltimore, MD 21205.ORCID 0000-0001-6755-8111
Anthony A JamesDepartment of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025.ORCID 0000-0001-5577-3308
Funding
Impact of gene-drive systems for population modification on malaria vector mosquitoesR01AI170692 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI DIMOPOULOS, GEORGE, JAMES, ANTHONY A. · 2023 to 2025
$3.2M
Bill & Melinda Gates Foundation INV-043645Gates Foundation INV-043645HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) AI170692NIAID NIH HHS R01 AI170692University of California, Irvine, Malaria Initiative NA
6 · The paper itself
Abstract
Gene-drive population modification strategies are being developed to control the transmission by anopheline mosquitoes of the parasites that cause human malaria. These approaches are designed to reduce disease prevalence and incidence by spreading dominant antiparasite effector genes throughout vector populations. The strains must sustain drive and parasite suppression properties over extended periods of time to have an epidemiological impact. Three gene-drive strains, AcTP13 and AcTP43 in
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Long-term stability and performance of Cas9/guide RNA-based gene drives in anopheline mosquitoes. · full record | OpenQuestion