Evidence map›Paper›PMID 42406466›Full record

ArticleACS synthetic biology2026

Genetic Biosensor for Optimizing Double-Stranded RNA Production by Bacteria.

Lucio Navarro-Escalante, Anthony J VanDieren, Jeffrey E Barrick

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS synthetic biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lucio Navarro-EscalanteDepartment of Microbiology, Genetics, & Immunology, Michigan State University, East Lansing, Michigan 48824, United States.
Anthony J VanDierenDepartment of Molecular Biosciences, The University of Texas at Austin, Austin, Texas 78712, United States.
Jeffrey E BarrickDepartment of Microbiology, Genetics, & Immunology, Michigan State University, East Lansing, Michigan 48824, United States.ORCID 0000-0003-0888-7358

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteria can be engineered to produce double-stranded RNA (dsRNA) molecules that induce a targeted RNA interference (RNAi) response in plants and animals for applications ranging from pest control to functional genomics. We developed a genetically encoded sensor that uses bimolecular fluorescence complementation to report relative dsRNA levels within bacterial cells. We tested sensor designs consisting of fusions of different dsRNA-binding domains derived from viruses to fragments of a split fluorescent protein in

Indexed as

Biosensing TechniquesRNA, Double-StrandedSerratiaAnimalsEscherichia coliRibonuclease IIIRNA InterferenceRibonuclease IIIRNA, Double-Strandedbimolecular fluorescence complementationGenetically encoded biosensorparatransgenesisRNA interferenceSerratia symbioticasymbiont-mediated RNAi

Identifiers

PMID42406466
PMCPMC13386644

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.