ArticleNano-micro letters2026
NIR and Oxidative Stress-Modulated Intestinal Peristalsis Motion of Tubular Conductive Thermo-Hydrogel Actuator.
Article in Nano-micro letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Actuators for soft bionic robotics, utilizing disease microenvironment-responsive and mechanically flexible materials, are influenced by intra- and intermolecular structures of hydrogels. However, they lack the required endogenous stimuli responsiveness necessary for applications like gastrointestinal-targeted drug screening and liquid/mass transport. Herein, a tubular conductive, reactive oxygen species (ROS)- and an near infrared (NIR)-responsive thermo-hydrogel actuator (THA) was fabricated for viscous liquid and solid transport. The presence of diselenide-crosslinked polymer dots (PDs) loaded onto polydopamine (PDA) nanoparticles (PD@PDA) in a poly(N-isopropylacrylamide) and polyvinyl alcohol (PNIPAM/PVA) matrix provided the necessary LCST alongside ROS- and NIR-responsive behavior. In the presence of high ROS, the diselenide bonds cleaved, resulting in release of PDA, generating NIR-specific actuation. The actuation process was confirmed by the directional movement of silicone oil (MR-200) and a small glass ball, which were selective to high ROS levels. The THA also demonstrated changes in electrical resistance (decrease in ΔR: ~ 14.60 kΩ), and stretchability (~ 127% increase in breaking strain), which may be used for screening-based applications. The THA demonstrated remarkable biocompatibility with Caco-2 (colon cancer) cells, alongside ROS scavenging and downregulation of TNF-α and IL-1β. Hence, this platform provides a viable pathway for fabricating bionic and biomimetic actuators for viscous liquid and solid transport.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.