Evidence map›Paper›PMID 42406152›Full record

ArticleArchives of women's mental health2026

Perinatal mental health issues in consultations regarding medication use during breastfeeding: Insights from the Japan Drug Information Institute in Pregnancy (JDIIP).

Sachi Koinuma, Yasuha Ogawa, Chie Kohno, Izumi Fujioka, Mikako Goto, Koushi Yamaguchi

Erratum issuedAbstract read
In one paragraph

Article in Archives of women's mental health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Sachi KoinumaJapan Drug Information Institute in Pregnancy, Integrated Center for Women's Health, National Center for Child Health and Development, Tokyo, Japan. koinuma-s@ncchd.go.jp.
Yasuha OgawaJapan Drug Information Institute in Pregnancy, Integrated Center for Women's Health, National Center for Child Health and Development, Tokyo, Japan.
Chie KohnoJapan Drug Information Institute in Pregnancy, Integrated Center for Women's Health, National Center for Child Health and Development, Tokyo, Japan.
Izumi FujiokaJapan Drug Information Institute in Pregnancy, Integrated Center for Women's Health, National Center for Child Health and Development, Tokyo, Japan.
Mikako GotoJapan Drug Information Institute in Pregnancy, Integrated Center for Women's Health, National Center for Child Health and Development, Tokyo, Japan.
Koushi YamaguchiJapan Drug Information Institute in Pregnancy, Integrated Center for Women's Health, National Center for Child Health and Development, Tokyo, Japan.

Funding

Health and Labour Sciences Research Grant from the Ministry of Health, Labour and Welfare, Japan 23KC2002
6 · The paper itself

Abstract

purposeWe comprehensively identified the challenges associated with psychotropic-medication use during breastfeeding in Japan and explored strategies to enhance breastfeeding support.

methodsWe analyzed breastfeeding-consultation records of cases involving postpartum mothers received by the Japan Drug Information Institute in Pregnancy (JDIIP) between February 2012 and March 2022, and corresponding questionnaire responses regarding the use of psychotropic medications. The "Perinatal Mental Health Consensus Guide" was used as a benchmark to examine temporal trends. To assess changes in consultation patterns over time, the study period was divided into a pre-publication (2012-2016) and post-publication phase (2017-2022).

results7,863 breastfeeding consultations were analyzed. Before and after the guide's publication, no significant difference was observed in the proportion related to mental disorders. Among consultations involving mental disorders, psychiatrists were the most common healthcare providers from whom advice had been sought before consultation, before and after the guide's publication, followed by obstetricians. Although approximately half of the healthcare providers had previously indicated that medication use during breastfeeding was possible, the proportion advising mothers to discontinue breastfeeding while taking psychotropic medications decreased after the guide's publication. Most mothers were prescribed multiple medications, with benzodiazepines being the most frequently discussed. However, the proportion of such consultations decreased significantly after the guide's publication.

conclusionsConsultations with specialized counseling agencies regarding psychotropic medication use during breastfeeding occurred at a consistent frequency regardless of guideline dissemination. While the guidelines' publication appears to have influenced healthcare providers' awareness, further examination is necessary to determine how best to provide information supporting breastfeeding.

Indexed as

Breast FeedingMental DisordersMothersPsychotropic DrugsReferral and ConsultationAdultFemaleHumansInfant, NewbornJapanMental HealthPerinatal CarePostpartum PeriodPregnancyPsychiatristsSurveys and QuestionnairesPsychotropic DrugsBreastfeedingJapanPerinatal mental healthPsychotropic medication

Identifiers

PMID42406152
PMCPMC13337846

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.