Evidence map›Paper›PMID 42406098›Full record

ArticleSurgical and radiologic anatomy : SRA2026

Foramen rotundum versus canal of the maxillary verve.

Mugurel Constantin Rusu, Diana Alexandra Bănică, Cătălin Constantin Dumitru, Adelina Maria Jianu, Răzvan Costin Tudose

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Article in Surgical and radiologic anatomy : SRA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Mugurel Constantin RusuDivision of Anatomy, Department 1, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 050474, Bucharest, Romania.
Diana Alexandra BănicăDivision of Anatomy, Department 1, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 050474, Bucharest, Romania.
Cătălin Constantin DumitruDivision of Anatomy, Department 1, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 050474, Bucharest, Romania.
Adelina Maria JianuDepartment of Anatomy and Embryology, Faculty of Medicine, "Victor Babeș" University of Medicine and Pharmacy, 300041, Timișoara, Romania. adelina.jianu@umft.ro.
Răzvan Costin TudoseDivision of Anatomy, Department 1, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 050474, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe foramen rotundum, located in the greater wing of the sphenoid bone, transmits the maxillary nerve (V2) from the middle cranial fossa to the pterygopalatine fossa. Despite its designation as a foramen, this structure possesses measurable length, suggesting it functions as a canal. While cross-sectional dimensions have been documented, canal length remains underreported. This study aimed to evaluate the morphometric characteristics of the foramen rotundum canal (FRC) using cone-beam computed tomography (CBCT).

methodsA retrospective study was conducted on CBCT scans of 45 adult patients (27 males, 18 females) acquired using an iCAT system. Multiplanar reconstructions were analysed using Planmeca Romexis software. Canal length was measured bilaterally from the intracranial to extracranial opening. Statistical analysis included paired and independent t-tests, Wilcoxon signed-rank and Mann-Whitney U tests, with significance set at p < 0.05.

resultsEighty-eight FRC measurements were analysed. Mean canal length was 4.07 ± 1.78 mm (range: 0.75-9.12 mm), with a coefficient of variation of 43.8%. The left side demonstrated significantly longer canals than the right (4.33 ± 1.77 mm vs. 3.81 ± 1.77 mm; p = 0.013). Males showed longer canals than females (4.22 ± 1.87 mm vs. 3.84 ± 1.65 mm), though not statistically significant (p = 0.325). One case with bilateral accessory foramina rotunda was identified and described separately.

conclusionsThe foramen rotundum demonstrates measurable canal-like dimensions with considerable variability and significant left-sided predominance. These findings support reconceptualising this structure as the FRC, with implications for skull base surgery and trigeminal interventions.

Indexed as

Cone-Beam Computed TomographyMaxillary NerveSphenoid BoneAdultAnatomic VariationCranial Fossa, MiddleCross-Sectional StudiesFemaleHumansMalePterygopalatine FossaRetrospective StudiesSex FactorsAnatomical variationCone-beam computed tomographyForamen rotundumMaxillary nerve canalPterygopalatine fossaSkull base morphometry

Identifiers

PMID42406098
PMCPMC13337921

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.