Evidence map›Paper›PMID 42406040›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026

Correction of aphakia using biometry-based contact lens calculation in pediatric cataract extraction: introducing the aphakic contact lens formula.

Christoph Lwowski, Klemens Paul Kaiser, Yaroslava Wenner, Navid Farassat, Thomas Kohnen, Wolf A Lagrèze

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Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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6 authors.

Christoph LwowskiDepartment of Ophthalmology, Goethe-University, Frankfurt am Main, Germany. lwowski@med.uni-frankfurt.de.ORCID http://orcid.org/0000-0003-4602-6655
Klemens Paul KaiserDepartment of Ophthalmology, Goethe-University, Frankfurt am Main, Germany.
Yaroslava WennerDepartment of Ophthalmology, Goethe-University, Frankfurt am Main, Germany.
Navid FarassatEye Center, Medical Center, Medical Faculty, University Hospital Freiburg, Freiburg im Breisgau, Germany.
Thomas KohnenDepartment of Ophthalmology, Goethe-University, Frankfurt am Main, Germany.
Wolf A LagrèzeEye Center, Medical Center, Medical Faculty, University Hospital Freiburg, Freiburg im Breisgau, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo develop and test a formula for contact lens calculation in aphakic infants. This formula, termed the "aphakic Contact Lens" (aCL) formula, utilizes preoperative axial length and keratometry data.

methodsThis retrospective, consecutive, two-center study used data derived from a development cohort (Freiburg, Germany) to create and optimize the aCL formula in aphakic eyes. A separate validation cohort (Frankfurt, Germany) was used to validate its predictive performance. The accuracy of the aCL formula was compared against: retinoscopy, a previously reported formula (Trivedi and Wilson, TW), and the use of a + 32.0 diopter (D) CL. Performance was evaluated using the prediction error (PE), absolute prediction error (AE) and the number of eyes within a certain range from retinoscopy (± 0.5D, ± 1.0D, ± 2.0D).

resultsThe aCL formula demonstrated comparable absolute prediction errors to retinoscopy (median AE 0.53D vs. 0.69D) and outperforms the TW formula or + 32D CL (median AE 3.25D and 2.63D). The number of eyes within ± 0.5D (38.3%) is lower compared to retinoscopy (50.0%), but comparable for ± 1.0D and better for ± 2.0D (61.7% vs. 66.7%, 83.3% vs. 72.2%). Both perform better than TW formula and + 32.0D (ranging from 0.0% for ± 0.5D to 33.3% for ± 2.0D).

conclusionsThe aCL formula is a reliable and accurate tool for determining CL power in aphakic infants. It performed superior to other formula-based and default strategies and is comparable to a retinoscopy. Still, follow-up studies with larger cohorts are needed to validate this outcome.

Indexed as

AphakiaCongenital cataractContact lensLens extractionRetinoscopy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.