Evidence map›Paper›PMID 42406028›Full record

ArticleNeuroradiology2026

Anterior cerebral artery variants and their influence on endovascular outcomes: a propensity score matched analysis from the CRETA registry.

Arturo Consoli, Raffaele Tortora, Frédéric Clarençon, Adam A Dmytriw, Eimad Shotar, Pascal Jabbour, Marios Psychogios, Peter Sporns, Ajit S Puri, Ameer E Hassan and 40 more

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Article in Neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

50 authors.

Arturo ConsoliDiagnostic and Interventional Neuroradiology Department, Foch Hospital, Suresnes, France.
Raffaele TortoraInterventional and Diagnostic Neuroradiology Unit - Azienda Ospedaliera Universitaria San Giovanni di Dio e Ruggi d'Aragona, Salerno, Italy.
Frédéric ClarençonDepartment of Neuroradiology, Pitié-Salpêtrière Hospital, Sorbonne University, APHP, 47, Bd de l'Hôpital, 75013, Paris, France.
Adam A DmytriwNeurovascular Centre, Divisions of Therapeutic Neuroradiology and Neurosurgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Eimad ShotarDepartment of Neuroradiology, Pitié-Salpêtrière Hospital, Sorbonne University, APHP, 47, Bd de l'Hôpital, 75013, Paris, France.
Pascal JabbourDepartment of Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, USA.
Marios PsychogiosDiagnostic and Interventional Neuroradiology, Universitätsspital Basel, Basel, Switzerland.
Peter SpornsDepartment of Radiology and Neuroradiology, Stadtspital, Zurich, Switzerland.
Ajit S PuriDivision of Neurointerventional Radiology, Department of Radiology, University of Massachusetts Medical Center, Worcester, USA.
Ameer E HassanEndovascular Surgical Neuroradiology, Valley Baptist Medical Center - Harlingen, Harlingen, USA.
Oktay AlginDepartment of Radiology, Ankara University, Ankara, Turkey.
Markus A MöhlenbruchInterventional Neuroradiology, Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany.
Riccardo RussoDepartment of Neuroscience, Neuroradiological Unit, University of Turin, Azienda Ospedaliera Città della Salute e della Scienza Hospital, Turin, Italy.
Oded GorenDepartment of Neurosurgery, Geisinger Health System, Danville, Pennsylvania, USA.
Gregoire BoulouisDepartment of Interventional Neuroradiology, Tours University Hospital, Tours, France.
Takeshi MorimotoDepartment of Clinical Epidemiology, Hyogo Medical University, Nishinomiya, Japan.
Raoul PopInterventional Neuroradiology Department, Strasbourg University Hospitals, Strasbourg, France.
Joanna Wk HoDepartment of Neurosurgery, Kwong Wah Hospital, Hong Kong, China.
Virginia Pujol LereisServicio de Neurología Vascular, Departamento de Neurología, Fleni, Argentina.
Jared CooperDepartment of Neurosurgery, Westchester Medical Center, New York, USA.
Giancarlo SalsanoUOC Neuroradiologia, Ospedale San Martino, Genova, Italy.
Alessandro SgrecciaDiagnostic and Interventional Neuroradiology Department, Foch Hospital, Suresnes, France.
Eytan RazDepartment of Radiology, NYU Langone Health, New York, New York, USA.
Julien BurelDepartment of Radiology, Rouen University Hospital, Rouen, Normandy, France.
Khawaja Muhammad Baqir HassanDepartment of Neuroradiology, Lahore General Hospital, Lahore, Pakistan.
Zhe JiDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Riitta RautioDepartment of Interventional Radiology, Turku University Hospital, Turku, Finland.
Maria RuggieroNeuroradiology Unit, AUSL Romagna, Cesena, Italy.
Valerio Da RosDepartment of Biomedicine and Prevention, University hospital of Rome "Tor Vergata", Rome, Italy.
Joseph Domenico GabrieliNeuroradiology Unit, Policlinico Universitario di Padova, Padova, Italy.
Michael LevittDepartment of Neurological Surgery, University of Washington, Washington, USA.
Antonio Armando CaraglianoNeuroradiology Unit, Biomedical Sciences and of Morphologic and Functional Images, AOU Policlinico G. Martino, Messina, Italy.
Christophe CognardService de Neuroradiologie Interventionnelle et Diagnostique, Hôpital Purpan- CHU Toulouse, Toulouse, France.
Gaultier MarnatNeuroradiology Department, Bordeaux University Hospital, Bordeaux, France.
Nicola LimbucciInterventional Neurovascular Unit, A.O.U. Careggi, Firenze, Italy.
Mariangela PianoNeuroradiology Unit, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy.
Alexis GuedonDepartment of Neuroradiology, AP-HP Nord, Hôpital Lariboisière, 75010, Paris, France.
Andrea RomiNeuroradiology Unit, IRCCS Policlinico San Matteo, 27100, Pavia, Italy.
Fortunato Di CaterinoDepartment of Interventional Neuroradiology, University Hospital Centre Besancon, Besançon, France.
Vyval MykolaResearch and Practical Centre for Endovascular Neuroradiology, the NAMS of Ukraine, Kyiv, Ukraine.
Ocílio Ribeiro GonçalvesFederal University of Piauí, Teresina, Brazil.
Adrien GuenegoDepartment of Diagnostic and Interventional Neuroradiology, Erasme University Hospital, Brussels, Belgium.
Mohamad AbdalkaderDepartment of Radiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.
Thanh NguyenDepartment of Radiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.
Vitor M PereiraNeurovascular Centre, Divisions of Therapeutic Neuroradiology and Neurosurgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Erwah KalsoumDepartment of Neuroradiology, Henri Mondor Hospital, Créteil, France.
Aldobrando BroccoliniUOC Neurologia, Fondazione Policlinico Universitario A.Gemelli IRCCS Roma, Rome, Italy.
Alessandro PedicelliUniversità Cattolica del Sacro Cuore, Roma, Italy.
Luca ScarciaDepartment of Neuroradiology, Henri Mondor Hospital, Créteil, France.
Andrea M AlexandreUOSD Neuroradiologia Interventistica, Fondazione Policlinico Universitario A.Gemelli IRCCS Roma, Rome, Italy. andrea.alexandre@policlinicogemelli.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnatomical variants of the anterior cerebral artery (ACA) may increase technical complexity during endovascular treatment of distal ACA aneurysms (DACA). However, their impact on treatment outcomes remains unclear. This study evaluated whether ACA variants influence angiographic and clinical outcomes following endovascular treatment.

methodsA retrospective multicenter analysis was conducted using data from the CRETA Registry, including patients with ruptured and unruptured DACA treated endovascularly. Patients were grouped according to ACA anatomy (variant vs. conventional). Outcomes were compared after propensity score matching (PSM) to adjust for confounders including age, aneurysm rupture status, dome-to-neck ratio, branch origin, and treatment type. The primary outcome was aneurysm occlusion at last follow-up based on the Raymond-Roy classification. Secondary outcomes included ischemic and hemorrhagic complications, vasospasm, and clinical outcome measured by the modified Rankin Scale (mRS).

resultsAfter PSM, 128 patients were included (64 per group). Among patients with available imaging follow-up (54 in the conventional group and 55 in the variant group), adequate occlusion rates were comparable between the variant and conventional ACA groups (81.5% vs. 85.5%; p = 0.600). No significant differences were observed in ischemic or hemorrhagic complications, vasospasm, or long-term clinical outcomes. Sensitivity analyses confirmed the robustness of the findings.

conclusionsACA anatomical variants do not adversely affect the safety or efficacy of endovascular treatment for DACA. With appropriate anatomical assessment and treatment selection, endovascular therapy remains effective even in the presence of complex ACA configurations.

Indexed as

AneursymAnterior cerebral arteryDACA endovascular treatmentDistal anterior cerebral artery

Identifiers

PMID42406028

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