Synthetic microbial communities: from theoretical exploration to applied innovation.

Ting Wang, Lingling Xiong, Xiaolian Shen, Jingting Sun, Qian Zhou, Kehui Xiong, Xiuling Ji

Abstract readReview

In one paragraph

Review in World journal of microbiology & biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ting WangFaculty of Life Science and Technology & Medical Faculty, Kunming University of Science and Technology, Kunming, 650500, China.

Lingling XiongFaculty of Life Science and Technology & Medical Faculty, Kunming University of Science and Technology, Kunming, 650500, China.

Xiaolian ShenFaculty of Life Science and Technology & Medical Faculty, Kunming University of Science and Technology, Kunming, 650500, China.

Jingting SunFaculty of Life Science and Technology & Medical Faculty, Kunming University of Science and Technology, Kunming, 650500, China.

Qian ZhouFaculty of Life Science and Technology & Medical Faculty, Kunming University of Science and Technology, Kunming, 650500, China.

Kehui XiongFaculty of Life Science and Technology & Medical Faculty, Kunming University of Science and Technology, Kunming, 650500, China.

Xiuling JiFaculty of Life Science and Technology & Medical Faculty, Kunming University of Science and Technology, Kunming, 650500, China. jixiuling1023@126.com.

Funding

National Natural Science Foundation of China 32560297Yunnan Key Laboratory of Intestinal Microbiota Transplantation Technological Innovation and Clinical Application 20254916CE340073

6 · The paper itself

Abstract

Synthetic microbial communities (SynComs), which are artificially designed microbial communities, have shown significant potential for application in agriculture, environmental remediation, and medicine. The research surrounding SynComs is rooted in a comprehensive understanding of the functional mechanisms of natural microbial communities, as well as the pressing need to enhance microbial functions through artificial design. The primary goal of SynComs is to achieve targeted functional outcomes, such as promoting plant growth, inhibiting pathogens, remediating polluted environments, and improving human health, through the thoughtful composition of microbial combinations. This paper systematically gathers and analyzes relevant literature concerning the design, construction, functional validation, and application of SynComs across various fields. It investigates their applications in agriculture, environmental science, and industry, to provide a valuable reference for both research and practical implementation. SynComs have made significant strides in understanding plant-microbe interactions, including elucidating microbial functions and their mechanisms of action, exploring interactions among microbes, and enhancing plant growth and stress resistance. However, research on SynComs continues to encounter considerable challenges. To fully harness their potential in advancing sustainable development goals, future studies should emphasize the standardization and systematization of research methodologies. Furthermore, a deeper integration of multi-omics technologies and strengthened interdisciplinary collaboration are essential.

Indexed as

Microbial ConsortiaMicrobiotaSynthetic BiologyAgricultureBacteriaEnvironmental Restoration and RemediationHumansPlant DevelopmentPlantsEnvironmental remediationInterdisciplinary collaborationPlant–microbe interactionsSustainable agricultureSynthetic microbial communities

Identifiers

PMID42406006

DOI10.1016/j.jmb.2015.10.019

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.