Evidence map›Paper›PMID 42406004›Full record

ArticleBrain imaging and behavior2026

Neuromelanin-sensitive MRI for identifying dopamine transporter imaging abnormality risk in idiopathic rapid eye movement sleep behavior disorder.

Jae Rim Kim, Beomseok Sohn, Jeong Won Jo, Hwan Heo, Soohwa Song, Eung Yeop Kim, Eun Yeon Joo

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Article in Brain imaging and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jae Rim Kim *Department of Neurology, Chungnam National University Sejong Hospital, Chungnam National University School of Medicine, Sejong, Republic of Korea.ORCID http://orcid.org/0000-0002-3404-199X
Beomseok Sohn *Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.ORCID http://orcid.org/0000-0002-6765-8056
Jeong Won JoHeuron Co., Ltd, Incheon, Korea.ORCID http://orcid.org/0000-0002-0915-4781
Hwan HeoHeuron Co., Ltd, Incheon, Korea.ORCID http://orcid.org/0000-0003-2144-6637
Soohwa SongHeuron Co., Ltd, Incheon, Korea.ORCID http://orcid.org/0000-0002-4723-5603
Eung Yeop Kim *Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea. neuroradkim@gmail.com.ORCID http://orcid.org/0000-0002-9579-4098
Eun Yeon Joo *Department of Neurology, Neuroscience Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea. ejoo@skku.edu.ORCID http://orcid.org/0000-0003-1233-959X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuromelanin-sensitive magnetic resonance imaging (NM-MRI) enables non-invasive assessment of the substantia nigra pars compacta (SNpc). However, its utility in identifying dopaminergic dysfunction in idiopathic rapid eye movement sleep behavior disorder (iRBD) remains unclear. This study evaluated NM-MRI alterations in the SNpc, stratified by dopamine transporter (DaT) imaging status, to assess its performance in detecting early dopaminergic alterations. This combined retrospective and prospective study included 66 patients with iRBD (45 males, 67.0 ± 6.3 years) and 30 healthy controls (HCs) (11 males, 63.6 ± 6.5 years). Patients with iRBD were divided based on

Indexed as

Dopamine Plasma Membrane Transport ProteinsMagnetic Resonance ImagingMelaninsREM Sleep Behavior DisorderAgedDopaminergic ImagingFemaleHumansMaleMiddle AgedPars CompactaPositron-Emission TomographyProspective StudiesRetrospective StudiesTropanes2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropaneDopamine Plasma Membrane Transport ProteinsMelaninsneuromelaninTropanesDopamine transporter imagingIdiopathic REM sleep behavior disorderNeuromelanin-sensitive MRI

Identifiers

PMID42406004
PMCPMC13337592

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.