Evidence map›Paper›PMID 42405980›Full record

ArticlePediatric radiology2026

Widely available, general-purpose generative AI applications for radiology education: determining the teaching quality of synthetic pediatric neuroradiology images.

Thomas P Reith, Donna M D'Alessandro, Krishnakumari A Modi, Mohammed Sabawi, Catherina S Zadeh, Mikhael G Sebaaly, Lillian M Lai, Takashi Shawn P Sato, Simon C Kao, Yutaka Sato and 1 more

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Article in Pediatric radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Thomas P ReithDepartment of Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA. thomas-reith@uiowa.edu.
Donna M D'AlessandroDepartment of Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Krishnakumari A ModiDepartment of Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Mohammed SabawiDepartment of Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Catherina S ZadehDepartment of Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Mikhael G SebaalyDepartment of Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Lillian M LaiDepartment of Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Takashi Shawn P SatoDepartment of Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Simon C KaoDepartment of Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Yutaka SatoDepartment of Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Michael P D'AlessandroDepartment of Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArtificial intelligence (AI) is increasingly incorporated into medical education. Widely available, general-purpose generative AI applications are increasingly capable of producing high-fidelity synthetic medical images, which may have potential educational uses.

objectiveTo assess the ability of widely available, general-purpose generative AI applications to produce synthetic pediatric neuroradiology images of teaching quality. MATERIALS AND

methodsTen significant diagnostic errors in pediatric neuroradiologic emergencies were identified and divided into 22 individual clinical scenarios. Two widely available, general-purpose generative AI applications, GPT-5 (OpenAI, San Francisco, CA) and Gemini 3 Pro with the Nano Banana Pro image-generation engine (Google, Mountain View, CA), were prompted to generate five separate images for each scenario, yielding a total of 220 images. Eight fellowship-trained pediatric radiologists independently assessed each image for teaching quality. Ratings were recorded and analyzed. Differences between applications were evaluated using Fisher's exact test.

resultsOverall, 8.6% of generated images (19/220) were deemed suitable for teaching by more than half of the pediatric radiologists. GPT-5 produced a higher proportion of acceptable images meeting this >50% criterion compared to Gemini 3 Pro (12.7% [14/110] vs. 4.5% [5/110]; P=0.031).

conclusionAt present, widely available, general-purpose generative AI applications should not be used to produce synthetic radiological images for educational purposes. Inaccuracies and inconsistencies limit reliability and may actively impair learning.

Indexed as

Generative adversarial networksGenerative AINeuroradiology

Identifiers

PMID42405980

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.