ArticleInvestigative and clinical urology2026
Trends in antimicrobial resistance of major gram-negative uropathogens, 2016-2024: A single center retrospective study.
Article in Investigative and clinical urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeResistance to empiric antimicrobials has become markedly higher among gram-negative uropathogens in Korea, compared to those in Europe and North America. To guide empiric treatment strategies and to build real evidence, we conducted a retrospective analysis of antimicrobial susceptibility patterns from urine cultures obtained at a university hospital. MATERIALS AND
methodsAntimicrobial susceptibility test (AST) results from initial positive urine cultures (n=11,358, both inpatients and outpatients) collected between 2016 and 2024 were reviewed. The analysis focused on predominant gram-negative isolates-
resultsBetween 2016 and 2024, AST identified
conclusionsThis 9-year longitudinal study reveals sharp cefepime resistance increases post-2019 and persistently high fluoroquinolone resistance among major four gram-negative uropathogens. Targeted antimicrobial stewardship are essential to optimize urinary tract infection management and reduce unnecessary broad spectrum antimicrobials in Korea.
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