Evidence map›Paper›PMID 42405674›Full record

ArticleInvestigative ophthalmology & visual science2026

Psychometric Performance of Children With Amblyopia During a Tablet-Based Adaptive Visual Acuity Assessment.

Jan Skerswetat, Zain Ahmed, Nikhil Chaudhry, Peter J Bex, Emily Wiecek

Abstract read
In one paragraph

Article in Investigative ophthalmology & visual science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Jan SkerswetatDepartment of Psychology, Northeastern University, Boston, Massachusetts, United States.
Zain AhmedDepartment of Ophthalmology, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, United States.
Nikhil ChaudhryDepartment of Ophthalmology, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, United States.
Peter J BexDepartment of Psychology, Northeastern University, Boston, Massachusetts, United States.
Emily WiecekDepartment of Ophthalmology, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, United States.

Funding

Eye Movement Rehabilitation in Low Vision PatientsR01EY029713 · NEI · NORTHEASTERN UNIVERSITY · PI BEX, PETER JOHN · 2019 to 2023
$1.9M
Spatial Frequency Dependent Deficits in Anisometropic AmblyopiaK23EY034212 · NEI · BOSTON CHILDREN'S HOSPITAL · PI Emily Wiecek · 2022 to 2026
$570k
NEI NIH HHS K23 EY034212NEI NIH HHS R01 EY029713
6 · The paper itself

Abstract

Purpose: Visual acuity is a key metric for the diagnosis of amblyopia. Here, we introduce a self-administered near visual acuity (VA) test using the Angular Indication Measurement paradigm (AIM-VA) and evaluate it in children with and without amblyopia. Methods: Thirty-five children (age range, 5-16 years; 20 males) with (n = 22) and without (n = 13) amblyopia monocularly completed the AIM-VA twice within the same day and a Snellen-VA test. The AIM-VA presented three 4 × 4 charts of Landolt-C optotypes that adaptively varied in size and had randomized gap orientations. Orientation report errors as a function of optotype size were fit with a one-parameter (VA) model or a three-parameter (VA, slope, and response error) model. Bland-Altman analysis assessed test-retest repeatability and intertest agreement with Snellen-VA. Linear correlations and leave-one-out analyses explored relationships between psychometric parameters across groups and amblyopia subtypes. Results: Interocular acuity difference (IOD) was significantly larger in children with amblyopia than in controls for both AIM-VA and Snellen-VA. The one-parameter AIM-VA yielded repeatability comparable to previous reports, particularly in the amblyopic group, and showed no significant test-retest bias (P > 0.05). However, there was a systematic mean bias of lower logMAR estimates relative to Snellen-VA in the amblyopic group (P = 0.002), likely reflecting the difference in testing distance and task. Exploratory analysis revealed that shallower psychometric slopes were consistently associated with larger noise values across groups, with stronger parameter covariance in refractive than strabismic amblyopia. Conclusions: AIM-VA successfully detected amblyopic near-vision IOD. The one-parameter AIM-VA model showed no retest bias and comparable variance in this pediatric population. Exploratory psychometric parameters showed promise as additional indicators of functional deficits, with potential phenotypical differences between amblyopia subtypes warranting further investigation. AIM-VA is an adaptive, self-administered task that may be an effective tool for managing amblyopia.

Indexed as

AmblyopiaComputers, HandheldPsychometricsVision TestsVisual AcuityAdolescentChildChild, PreschoolFemaleHumansMaleReproducibility of Results

Identifiers

PMID42405674
PMCPMC13348929

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.