Evidence map›Paper›PMID 42405533›Full record

ArticleVascular medicine (London, England)2026

Initiation of an emergency department discharge pathway for low-risk patients with venous thromboembolism: Factors impact real-world practice.

William B Stubblefield, James Barclay, Jesse O Wrenn, Doug Conway, Scott Nelson, Quinn S Wells, Dario Giuse, Zhao Zuo, Alexandra M Baird, Tyler Barrett and 5 more

Abstract read
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In one paragraph

Article in Vascular medicine (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

William B StubblefieldDepartment of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0003-3817-1414
James BarclayVanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.
Jesse O WrennDepartment of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Doug ConwayVanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.
Scott NelsonDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0002-1941-1817
Quinn S WellsDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.
Dario GiuseDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.
Zhao ZuoDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.
Alexandra M BairdHCA Healthcare, Cardiac and Vascular Service Line, Nashville, TN, USA.
Tyler BarrettDepartment of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Shi HuangDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Karen BeauchampBristol Myers Squibb, Princeton, NJ, USA.
Alan B StorrowDepartment of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Sean P CollinsDepartment of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Joshua A BeckmanDivision of Vascular Medicine, UT Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0001-8332-8439

Funding

Vanderbilt Interdisciplinary Hospital-Based Systems of Care Research and Training ProgrAm (VISTA)T32HL170986 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SUNIL KRIPALANI, ALAN B STORROW · 2024 to 2026
$1.3M
NHLBI NIH HHS T32 HL170986
6 · The paper itself

Abstract

backgroundWe initiated an institutional pathway for the outpatient treatment of low-risk patients with venous thromboembolism (VTE) and evaluated emergency department (ED) discharge rates and safety outcomes before and after pathway initiation. This pathway was augmented by the ability to schedule a 1-week follow-up with an outpatient provider in a vascular medicine clinic, a 30-day direct oral anticoagulant (DOAC) prescription, and anticoagulant education facilitated by the ED clinical pharmacist.

methodsA retrospective cohort of 1260 patients with VTE presenting to the ED between July 1, 2014, and June 30, 2018, was identified in the electronic health record (EHR) by a natural language processing algorithm scanning radiology reports for the presence or absence of pulmonary embolism (PE) or deep venous thrombosis (DVT). We compared patients who presented 2 years before and 2 years after pathway initiation (July 1, 2016) using a regression model to examine the independent effect of ED pathway initiation on discharge rates.

resultsPatients with VTE before (

conclusionsInitiation of a VTE discharge pathway was complicated by an increase in the proportion of patients with recent hospitalizations and prior PE in the postpathway period, which was associated with lower odds of ED discharge.

Indexed as

Ambulatory CareAnticoagulantsCritical PathwaysEmergency Service, HospitalPatient DischargePulmonary EmbolismVenous ThromboembolismVenous ThrombosisAgedEmergency Room VisitsFemaleHumansMaleMiddle AgedRetrospective StudiesRisk AssessmentAnticoagulantsdeep vein thrombosis (DVT)direct oral anticoagulantsimplementation scienceoutpatientpulmonary embolism (PE)quality improvementvenous thromboembolism (VTE)

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.