ArticleSAGE open medicine2026
Association between clinical features of isolated coronary artery ectasia and circulating levels of inflammatory markers.
Article in SAGE open medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and aims: Coronary artery ectasia (CAE) can lead to adverse clinical outcomes, including coronary spasm, thrombosis, dissection and myocardial ischaemia. In patients with isolated CAE- in the absence of coronary artery stenosis, clinical symptoms such as angina pectoris may still occur. This study aimed to investigate the relationship between clinical features and circulating inflammatory marker levels in patients with isolated CAE. Methods: Patients undergoing coronary angiography (CAG) who consented to participate underwent cardiovascular disease and risk assessment. The study enrolled 52 patients with isolated CAE and 25 control individuals with normal coronary angiograms. Coronary blood flow in the three groups was assessed using the Thrombolysis in Myocardial Infarction (TIMI) frame count. Levels of inflammatory markers-including C-reactive protein (CRP), interleukin-1β (IL-1β), interleukin-8 (IL-8), IL-10 and tumor necrosis factor-alpha (TNF-α) - were measured in the circulating blood of symptomatic and asymptomatic patients with isolated CAE and compared between the two groups. Results: Symptomatic patients with isolated CAE showed significantly higher circulating levels of IL-1β and TNF-α than asymptomatic patients ( Conclusions: In patients with isolated CAE, the presence of symptoms is associated with elevated circulating levels of pro-inflammatory markers such as IL-1β and TNF-α, as well as reduced coronary blood flow.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.