Evidence map›Paper›PMID 42405292›Full record

ArticleACG case reports journal2026

Life-Threatening Variceal Bleeding in Antisynthetase Syndrome: Nodular Regenerative Hyperplasia and Porto-Sinusoidal Vascular Disorder.

Jazmin Mexia Cabrales, Hassan Sinan, Bibhuti Adhikari, Harleen Sidhu, Anastasia Novikov, Aaron Walfish

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jazmin Mexia CabralesDepartment of Internal Medicine, NYC Health + Hospitals/Elmhurst, Icahn School of Medicine at Mount Sinai, Elmhurst, NY.ORCID https://orcid.org/0000-0001-7889-492X
Hassan SinanDepartment of Internal Medicine, NYC Health + Hospitals/Elmhurst, Icahn School of Medicine at Mount Sinai, Elmhurst, NY.
Bibhuti AdhikariDepartment of Internal Medicine, NYC Health + Hospitals/Elmhurst, Icahn School of Medicine at Mount Sinai, Elmhurst, NY.
Harleen SidhuDepartment of Internal Medicine, NYC Health + Hospitals/Elmhurst, Icahn School of Medicine at Mount Sinai, Elmhurst, NY.
Anastasia NovikovDepartment of Gastroenterology, NYC Health + Hospitals/Elmhurst, Icahn School of Medicine at Mount Sinai, Elmhurst, NY.
Aaron WalfishDepartment of Gastroenterology, NYC Health + Hospitals/Elmhurst, Icahn School of Medicine at Mount Sinai, Elmhurst, NY.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antisynthetase syndrome (ASyS) is an autoimmune disorder that may be associated with hepatic involvement, such as nodular regenerative hyperplasia (NRH), a histologic manifestation of porto-sinusoidal vascular disorder, and complications such as variceal bleeding despite preserved liver function. We report a case of life-threatening variceal hemorrhage due to NRH-associated porto-sinusoidal vascular disorder in a patient with ASyS. This case highlights NRH as a cause of severe gastrointestinal bleeding in ASyS and underscores the need for diagnostic and management strategies distinct from those used in cirrhosis.

Indexed as

antisynthetase syndromenodular regenerative hyperplasiaporto-sinusoidal vascular disorder

Identifiers

PMID42405292
PMCPMC13331416

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.