Evidence map›Paper›PMID 42405258›Full record

Observational studyPeerJ2026

Prenatal corticosteroid use improves the severity and complications of necrotizing enterocolitis in preterm infants: a retrospective multicenter clinical study in China.

Chengyu Wang, Na Zhuo, Yanbin An, Arigonggaowa Arigong, Cheng Cai, Jia Wang, Jinglin Xu, Fan He, Jiexia Gao, Bowen Weng and 3 more

Abstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in PeerJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Chengyu Wang *Inner Mongolia Medical University, Hohhot, China.
Na Zhuo *Inner Mongolia Medical University, Hohhot, China.
Yanbin AnDepartment of Neonatology, Inner Mongolia Maternity and Child Health Care Hospital, Hohhot, China.
Arigonggaowa ArigongInner Mongolia Medical University, Hohhot, China.
Cheng CaiDepartment of Neonatology, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Jia WangDepartment of Neonatology, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Jinglin XuDepartment of Neonatology, Quanzhou Maternity and Children's Hospital, Quanzhou, China.
Fan HeNeonatal Intensive Care Unit, Jiangxi Provincial Children's Hospital, Nanchang, China.
Jiexia GaoDepartment of Neonatology, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Bowen WengDepartment of Neonatology, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Jiahuai LiuDepartment of Neonatology, Quanzhou Maternity and Children's Hospital, Quanzhou, China.
Cong YuNeonatal Intensive Care Unit, Jiangxi Provincial Children's Hospital, Nanchang, China.
Dongmei ChenDepartment of Neonatology, Quanzhou Maternity and Children's Hospital, Quanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our study is a retrospective multicenter observational cohort study to investigate effect of the use of antenatal corticosteroids (ACS) in preterm infants on the severity of necrotizing enterocolitis (NEC) and its associated complications. We collected clinical data from 443 preterm infants with gestational age (GA) of less than 37 weeks who were diagnosed with NEC in four hospitals across various provinces in China, covering the period from June 2020 to June 2024. According to whether they received a full course of prenatal corticosteroid treatment in the week before delivery, infants were divided into the exposed group and the unexposed group. A total of 213 preterm infants (48.08%) had received ACS therapy. When compared to the non-exposed group, the severity of NEC in the exposed group demonstrated a statistically significant difference (

Indexed as

Adrenal Cortex HormonesEnterocolitis, NecrotizingPrenatal CareChinaFemaleGestational AgeHumansInfant, NewbornInfant, PrematureMalePregnancyRetrospective StudiesSeverity of Illness IndexAdrenal Cortex HormonesNecrotizing enterocolitisPrenatal corticosteroidsPreterm infantsProtective effectSeverity

Identifiers

PMID42405258
PMCPMC13332717

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.