ArticleRSC advances2026
Lab-on-a-tip platform with cotton matrices for colorimetric detection of carmine in lipsticks.
Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carmine is a natural red dye derived from cochineal insects and is widely used in cosmetics and food products. Since carmine is derived from insects, individuals who follow vegan or vegetarian lifestyles and those who have religious beliefs may wish to ascertain its presence in the products they use. Additionally, carmine causes angioedema, urticaria, contact dermatitis, systemic anaphylaxis and even asthma in hypersensitive individuals. Conventional methods for detecting the presence of carmine require expensive equipment and skilled personnel; thus, robust, low-cost and rapid detection is needed. In this work, we fabricated a simple lab-on-a-tip device with reagents imbibed in two cotton matrices for the colorimetric detection of carmine. In this assay, carmine reacts with hydrochloric acid to produce carminic acid, which further reacts with ferric chloride to form a brown chromogenic complex whose intensity is proportional to the carmine concentration. Additionally, a comparative evaluation was performed between cotton and filter paper, in which cotton exhibited enhanced color intensity and sensitivity because of its three-dimensional intertwined fibrous network. The simple lab-on-a-tip device provides a reproducible and distinguishable color across the selected concentration range, with an experimentally determined limit of detection (LOD) of 0.5 mg mL
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.