ArticleFrontiers in public health2026
Epidemiological characteristics of human parainfluenza virus infection in hospitalized children: a single-center study.
Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aims to investigate the epidemiological characteristics of human parainfluenza virus (HPIV) infections in hospitalized children with acute respiratory tract infections (ARTIs) at a single center in Shanghai, and to provide scientific evidence for optimizing diagnostic and therapeutic strategies for pediatric ARTIs. Methods: A retrospective study was conducted on 29,260 children hospitalized with ARTIs at Shanghai Children's Hospital between January 2021 and December 2024. The study analyzed the sex distribution, age-specific patterns, seasonal variations, and coinfection characteristics of HPIV infections. Results: Among the 29,260 children with ARTIs, the overall detection rate of HPIV was 5.1% (1,487/29,260). The highest positivity rates were observed in children aged <1 year (7.4%) and 1-3 years (8.1%), while the lowest was in those aged 13-18 years (1.7%; overall Conclusion: HPIV is a significant cause of hospitalization for ARTIs in children in Shanghai, especially among those under 3 years of age, with a distinct seasonal peak in summer. Mixed HPIV infections, particularly with rhinovirus and
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