Evidence map›Paper›PMID 42404839›Full record

ArticleStroke (Hoboken, N.J.)2026

Standardizing Global Pediatric Stroke Pathways: Insights From a Global Survey Conducted by the Society of Neurointerventional Surgery Pediatric Special Interest Group.

Mesha Martinez, Aaron Rodriguez-Calienes, Alhamza R Al-Bayati, Joseph J Gemmete, Todd Abruzzo, Karen Chen, Daniel L Cooke, Lucas Elijovich, Johanna T Fifi, Michael T Froehler and 13 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stroke (Hoboken, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Mesha MartinezNeurointerventional Radiology, Clarity Brain and Spine, Cedar Park, TX (M.M.).ORCID https://orcid.org/0000-0003-3643-4401
Aaron Rodriguez-CalienesDepartment of Neurology, University of Miami Miller School of Medicine/Jackson Health System, FL (A.R.-C.).ORCID https://orcid.org/0000-0002-8413-6954
Alhamza R Al-BayatiDepartment of Neurology, University of Pittsburgh Medical Center, PA (A.R.A.-B.).ORCID https://orcid.org/0000-0001-8103-1930
Joseph J GemmeteDepartments of Radiology and Neurosurgery, University of Michigan Health System, Northville (J.J.G.).
Todd AbruzzoPediatric Neuroendovascular Therapy, Paradise Valley, AZ (T.A.).
Karen ChenDepartment of Radiology, Texas Children's Hospital, Houston (K.C.).ORCID https://orcid.org/0000-0002-5034-3867
Daniel L CookeDepartment of Radiology and Biomedical Imaging, University of California, San Francisco (D.L.C., S.W.H.).ORCID https://orcid.org/0000-0002-3694-413X
Lucas ElijovichDepartment of Neurology and Neurosurgery, Semmes-Murphey Clinic, Memphis, TN (L.E.).
Johanna T FifiDepartments of Neurosurgery, Neurology, and Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (J.T.F.).ORCID https://orcid.org/0000-0001-7786-5668
Michael T FroehlerDepartment of Neurology, Vanderbilt University Medical Center, Nashville, TN (M.T.F.).
Steven W HettsDepartment of Radiology and Biomedical Imaging, University of California, San Francisco (D.L.C., S.W.H.).ORCID https://orcid.org/0000-0001-5885-7259
Peter KanDepartment of Neurosurgery, University of Texas Medical Branch, Galveston (P.K.).ORCID https://orcid.org/0000-0001-6649-4128
Prakash MuthusamiDiagnostic Imaging, The Hospital for Sick Children, Toronto, ON, Canada (P.M., C.P.-F.).ORCID https://orcid.org/0000-0002-7062-9571
Gary M NesbitDepartment of Interventional Neuroradiology, Oregon Health and Science University, Portland (G.M.N.).
Darren B OrbachNeurointerventional Radiology (D.B.O.), Boston Children's Hospital, MA.ORCID https://orcid.org/0000-0002-1793-3398
Aditya S PandeyDepartment of Neurosurgery (A.S.P.), University of Michigan, Ann Arbor.ORCID https://orcid.org/0000-0003-0789-4273
Carmen Parra-FarinasDiagnostic Imaging, The Hospital for Sick Children, Toronto, ON, Canada (P.M., C.P.-F.).ORCID https://orcid.org/0000-0002-6444-2188
Monica Smith PearlDepartment of Radiology, Children's National Hospital, Baltimore, MD (M.S.P.).ORCID https://orcid.org/0000-0001-9514-8902
Adam RennieInterventional Neuroradiology, Great Ormond Street Hospital, London, United Kingdom (A.R.).
Alfred Pokmeng SeeDepartment of Neurosurgery (A.P.S.), Boston Children's Hospital, MA.ORCID https://orcid.org/0000-0003-3634-4692
Ali ShaibaniDepartment of Radiology, Ann and Robert H. Lurie Children's Hospital of Chicago, IL (A.S.).
Neeraj ChaudharyDepartment of Radiology (N.C.), University of Michigan, Ann Arbor.ORCID https://orcid.org/0000-0003-0630-2547
Santiago Ortega-GutierrezDepartment of Neurology, University of Iowa Hospitals and Clinics (S.O.-G.).ORCID https://orcid.org/0000-0002-3408-1297

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate global stroke pathways in pediatric acute ischemic stroke care, including availability of personnel, imaging practices, hyperacute therapies available, and institutional resources.

methodsA 25-question survey designed by the Society of Neurointerventional Surgery Pediatric Special Interest Group was distributed internationally via pediatric and neurointerventional societies. The survey collected data on institutional settings, stroke team composition, imaging protocols, use of artificial intelligence, and access to thrombectomy and thrombolysis. Responses from 103 stroke care providers were analyzed using descriptive statistics. Participation was voluntary and anonymous, and >1 respondent from the same institution was permitted.

resultsNinety-one of 103 respondents (88%) reported managing pediatric acute ischemic stroke. However, only 65% offered both intravenous thrombolysis and thrombectomy. Computed tomography and computed tomography angiography were the most commonly used first-line imaging modality (34%), whereas perfusion imaging and artificial intelligence tools were underutilized. Pediatric neurologists were the most common decision-makers for thrombolysis (38%). Posterior circulation thrombectomy was widely unavailable (offered at only 45% of centers).

conclusionsSurvey results revealed considerable variability in pediatric acute ischemic stroke pathways globally and a lack of standardization in treatment. Disparities in access to imaging, hyperacute therapies, and trained personnel underscore the need for standardization, international collaboration, and the creation of systems utilizing available resources to improve pediatric stroke care.

Indexed as

artificial intelligenceischemic strokethrombectomythrombolytic therapytomography

Identifiers

PMID42404839
PMCPMC13331382

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.