Evidence map›Paper›PMID 42404693›Full record

ArticleDepression and anxiety2026

Age Differences in Factors Associated With Insomnia Severity: A Comparative Study of Questionnaire Scores and Heart Rate Variability Parameters.

Kong Xinyu, Guo Xiaodan, Wang Mengmeng, Zhang Haodong, Xiao Fulong

Abstract readComparative Study
In one paragraph

Article in Depression and anxiety, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Kong XinyuDepartment of Sleep Medicine, Peking University People's Hospital, Beijing, China, pku.edu.cn.
Guo XiaodanDepartment of Sleep Medicine, Peking University People's Hospital, Beijing, China, pku.edu.cn.
Wang MengmengNursing Department, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China, zju.edu.cn.
Zhang HaodongDepartment of Sleep Medicine, Peking University People's Hospital, Beijing, China, pku.edu.cn.
Xiao FulongDepartment of Sleep Medicine, Peking University People's Hospital, Beijing, China, pku.edu.cn.ORCID https://orcid.org/0000-0001-5933-4249

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Primary insomnia exhibits diverse clinical profiles across age groups, yet the underlying mechanisms remain unclear. This study aimed to explore age-related differences in factors associated with insomnia severity. Methods: Evaluating questionnaire scores and heart rate variability (HRV) parameters in young adult age (18-44 years, Results: Significant between-group differences were observed in Morningness-Eveningness Questionnaire (MEQ) scores and State-Trait Anxiety Inventory (STAI) state anxiety scores, with young adult patients showing a higher prevalence of evening chronotype. All HRV parameters except high-frequency (HF) power differed significantly between age groups, indicating age-related autonomic dysregulation. Regression analyses identified distinct predictors of insomnia severity: insomnia severity in young adults was independently associated with depressive symptoms and chronotype, whereas that in older adults was predicted by anxiety symptoms and HRV parameters reflecting autonomic imbalance (low-frequency [LF]/HF ratio, mean R-R intervals [RRIs]). Conclusion: These findings highlight age-dependent associations between insomnia severity, psychological factors, and autonomic function, suggesting that young adult insomnia may be more linked to depressive symptoms and chronotype, whereas old adult insomnia is strongly associated with anxiety and autonomic imbalance. This may inform age-tailored therapeutic strategies for primary insomnia.

Indexed as

AnxietyAutonomic Nervous SystemHeart RateSleep Initiation and Maintenance DisordersAdolescentAdultAge FactorsChronotypeDepressionFemaleHumansMaleMiddle AgedSeverity of Illness IndexSurveys and QuestionnairesYoung Adultage differencesautonomic nervous systemheart rate variabilityprimary insomniaquestionnaire scores

Identifiers

PMID42404693
PMCPMC13329830

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.