ReviewHealth science reports2026
Negative Pressure Wound Therapy for the Prevention of Wound Complications After Hepatopancreatobiliary Surgery: A Systematic Review and Meta-Analysis.
Review in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Hepatopancreatobiliary (HPB) surgeries, such as hepatic resection and pancreaticoduodenectomy, are associated with a high incidence of postoperative wound complications, particularly surgical site infections (SSIs). Negative pressure wound therapy (NPWT) has been proposed to reduce such complications, but its effectiveness in HPB surgery remains uncertain. This systematic review and meta-analysis aimed to evaluate the association between NPWT and postoperative wound complications following HPB procedures. Methods: We systematically searched PubMed, EMBASE, Cochrane Library, Web of Science, and Scopus through August 17, 2024 for randomized controlled trials (RCTs) and observational studies comparing NPWT with standard surgical dressing (SSD) after HPB surgery. Primary outcomes were overall, superficial, deep, and organ-space SSIs. Secondary outcomes included seroma, hematoma, wound dehiscence, and hospital readmission. Risk ratios (RRs) with 95% confidence intervals (CIs) were pooled using a random-effects model. Results: Eleven studies (7 RCTs, 4 observational; Conclusions: NPWT may reduce postoperative SSIs following HPB surgeries, particularly in patients undergoing pancreatectomy. However, the observed benefit was less robust in RCT-only analyses, and evidence for liver surgery remains limited. Further high-quality RCTs are needed to validate these findings.
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Registered trials
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