ArticleRevista panamericana de salud publica = Pan American journal of public health2026
Factors associated with laboratory confirmation of suspected hantavirus pulmonary syndrome in southern Argentina: a retrospective observational case-control study.
Article in Revista panamericana de salud publica = Pan American journal of public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To identify demographic, occupational, exposure, clinical, and laboratory factors independently associated with diagnostic confirmation of hantavirus infection by RT-PCR or IgM among patients with suspected hantavirus pulmonary syndrome evaluated in Río Negro and Neuquén, Argentina. Methods: A retrospective case-control study using emergency department records and epidemiological notification forms from public hospitals in Río Negro and Neuquén, Argentina, during 1996-2025. Cases were patients with suspected hantavirus pulmonary syndrome confirmed by RT-PCR detection of hantavirus RNA and/or hantavirus-specific IgM ELISA through a standardized laboratory confirmation pathway verified by the reference laboratory. Controls were suspected cases in whom hantavirus infection was ruled out through the same pathway. Demographic, occupational, exposure, clinical, laboratory, and chest radiography variables were analyzed. Logistic regression models were adjusted for age and sex; symptoms were mutually adjusted in the clinical block. Results: We included 325 suspected cases: 113 confirmed and 212 ruled out. Compared with no evident risk, the activity-based exposure scale showed strong associations for high-risk activity (aOR 156; 95% CI [10, 2 448]) and moderate-risk activity (aOR 33; 95% CI [2.4, 456]). Confirmed cases more often had elevated hematocrit (aOR 7.40; 95% CI [3.96, 13.8]), elevated lactate dehydrogenase (aOR 10.67; 95% CI [4.85, 23.3]), thrombocytopenia (aOR 11.08; 95% CI [5.59, 21.9]), and elevated creatinine (aOR 2.91; 95% CI [1.59, 5.34]). Severe respiratory failure/criteria for mechanical ventilation (aOR 5.58; 95% CI [3.16, 9.85]) and neurological symptoms (aOR 5.17; 95% CI [1.16, 28.0]) were independently associated with confirmation. Conclusions: Among patients with suspected hantavirus pulmonary syndrome evaluated in southern Argentina, structured exposure assessment and selected laboratory abnormalities were associated with laboratory confirmation. Given the study limitations, these hypothesis-generating findings may inform future development and prospective validation of clinical prediction tools.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.