Evidence map›Paper›PMID 42404463›Full record

ArticleSurgical neurology international2026

Spontaneous intradural extramedullary hematoma after mild exercise in Von Willebrand disease: A rare clinical presentation and literature review.

Ali Bukhari, Apostolos Lagaras, Muhammad Dherijha, Asad Malik, Abbas Shahid

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PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical neurology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ali BukhariDepartment of Trauma and Orthopaedics, Stepping Hill Hospital, Stockport, United Kingdom.
Apostolos LagarasDepartment of Trauma and Orthopaedics,, Salford Royal Hospital, Greater Manchester, United Kingdom.
Muhammad DherijhaDepartment of Neurosurgery, Salford Royal Hospital, Greater Manchester, United Kingdom.
Asad MalikDepartment of Trauma and Orthopaedics, Royal Oldham Hospital, Oldham, United Kingdom.
Abbas ShahidDepartment of Trauma and Orthopaedics, Royal Blackburn Teaching Hospital, Lancashire, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Von Willebrand disease (VWD) is the most common inherited bleeding disorder. Spinal intradural extramedullary hematoma (SIEH) is an exceptionally rare manifestation. Case Description: A 28-year-old woman with VWD developed spontaneous SIEH following mild exercise, presenting with back pain, progressive lower limb weakness, and double incontinence. Magnetic resonance imaging (MRI) demonstrated a T3/4 intradural extramedullary hematoma. Urgent surgical evacuation through T3/4 fenestration was performed, followed by targeted hemostatic therapy with recombinant von Willebrand factor (Vonicog Alfa). The patient made a complete neurological recovery within 3 months and remained asymptomatic at 14-month follow-up. Conclusion: SIEH should be considered in VWD patients presenting with acute spinal symptoms, even without trauma. Early MRI, prompt decompression, and tailored coagulation management are critical to optimal outcomes.

Indexed as

Spinal cord compressionSpinal subdural hematomaSurgical decompressionThoracic vertebraeVon Willebrand disease

Identifiers

PMID42404463
PMCPMC13331167

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