Evidence map›Paper›PMID 42404455›Full record

ArticleSurgical neurology international2026

From shunt dependency to shunt freedom: Endoscopic third ventriculostomy in ventriculoperitoneal shunt-dependent communicating tetraventricular hydrocephalus: A case report.

Dario Palescandolo, Sohaib A Korai, Alessandro Melatini, Marilena Rolli, Domenico Cassitto, Alessandra Giaquinta, Francesco Mastromatteo, Manfredo Esposito, Kumail Ali, Haleema Sadia and 2 more

Abstract readCase Reports
In one paragraph

Article in Surgical neurology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dario PalescandoloDepartment of Neurosurgery , Hospital Vito Fazzi ASL Lecce, Lecce, Italy.
Sohaib A KoraiDepartment of Neurosurgery , Hospital Vito Fazzi ASL Lecce, Lecce, Italy.
Alessandro MelatiniDepartment of Neurosurgery , Hospital Vito Fazzi ASL Lecce, Lecce, Italy.
Marilena RolliDepartment of Neurosurgery , Hospital Vito Fazzi ASL Lecce, Lecce, Italy.
Domenico CassittoDepartment of Neurosurgery , Hospital Vito Fazzi ASL Lecce, Lecce, Italy.
Alessandra GiaquintaDepartment of Neurosurgery , Hospital Vito Fazzi ASL Lecce, Lecce, Italy.
Francesco MastromatteoDepartment of Neurosurgery , Hospital Vito Fazzi ASL Lecce, Lecce, Italy.
Manfredo EspositoDepartment of Neurosurgery , Hospital Vito Fazzi ASL Lecce, Lecce, Italy.
Kumail AliDepartment of Precision Medicine, Division of Human Anatomy, Neuronal Networks Morphology and Systems Biology Lab, Department of Mental and Physical Health and Preventive Medicine, University of Campania "Luigi Vanvitelli, Naples, Italy.
Haleema SadiaDepartment of Precision Medicine, Division of Human Anatomy, Neuronal Networks Morphology and Systems Biology Lab, Department of Mental and Physical Health and Preventive Medicine, University of Campania "Luigi Vanvitelli, Naples, Italy.
Pierluigi FerraroDepartment of Neurosurgery , Hospital Vito Fazzi ASL Lecce, Lecce, Italy.
Cosimo D GianfredaDepartment of Neurosurgery , Hospital Vito Fazzi ASL Lecce, Lecce, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hydrocephalus represents pathological dilatation of the ventricular system caused by impaired cerebrospinal fluid (CSF) circulation and absorption, resulting in increased intracranial pressure. Ventriculoperitoneal shunting (VPS) remains the standard treatment for communicating hydrocephalus; however, it is associated with significant long-term complications, including infection and mechanical failure. Endoscopic third ventriculostomy (ETV), traditionally indicated for obstructive hydrocephalus, has increasingly been explored in selected cases of complex and communicating hydrocephalus. Case Description: We report the case of a 28-year-old male with tetraventricular hydrocephalus secondary to childhood craniofacial trauma, initially managed with VPS placement in childhood. His clinical course was complicated by multiple shunt revisions due to recurrent infections and valve malfunction. During a prolonged hospital admission for shunt infection and distal peritonitis, repeated failures of temporary CSF diversion occurred despite external ventricular drainage and prolonged antimicrobial therapy. Brain magnetic resonance imaging with CSF flow studies demonstrated persistent tetraventricular hydrocephalus with preserved aqueductal patency, consistent with a communicating hydrocephalus pattern. Following confirmation of CSF sterility, ETV was performed as a definitive treatment strategy. Conclusion: The procedure was completed without complications and resulted in progressive radiological resolution of hydrocephalus and sustained clinical improvement. The patient was discharged neurologically intact and free of permanent CSF diversion. This case highlights the potential role of ETV as a viable alternative to repeated shunt revisions in selected adult patients with communicating and tetraventricular hydrocephalus and underscores the need to reconsider traditional treatment paradigms in complex hydrocephalus management.

Indexed as

Communicating hydrocephalusEndoscopic third ventriculostomyPost-traumatic hydrocephalusVentriculoperitoneal shunt

Identifiers

PMID42404455
PMCPMC13331170

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.