Evidence map›Paper›PMID 42404380›Full record

ArticleEngineering biology

Engineering Biology's Vital Role for Climate Mitigation.

Lionel John Clarke

Abstract read
In one paragraph

Article in Engineering biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Lionel John ClarkeDepartment of BioEngineering Imperial College London UK.ORCID https://orcid.org/0000-0002-6841-6868

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper examines the potential role of engineering biology in contributing to climate mitigation through the de-fossilisation of fuels, chemicals, materials and food systems. Although significant progress is being made in de-fossilising energy via renewable electricity generation, other more carbon-centric sectors-notably transport, chemicals and agriculture-remain predominantly fossil-based. Despite sustained policy support, biofuels currently supply just 3.5% of global transport energy demand, whereas sustainable aviation fuel remains below 1% of global jet fuel supply. Similarly, only around 1% of plastics and polymers are bio-based. Replacing fossil carbon with renewable carbon remains a significant commercial challenge. Constraints include feedstock availability, sustainability concerns, capital intensity, certification requirements and policy uncertainty. The paper discusses how engineering biology-encompassing advances in synthetic biology, bioprocess engineering and electro-biological systems-may offer potentially transformative technological options and innovative commercial opportunities. It concludes that the contribution of engineering biology to climate mitigation will depend not on technical developments and investment alone but also on their integration into economically viable supply chains and the presence of stable long-term policy frameworks supporting investment and deployment at scale.

Identifiers

PMID42404380
PMCPMC13329841

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.