ArticleJournal of current ophthalmology
Systemic Hemodynamics and Ocular Perfusion in Normal-Tension Glaucoma: Evaluation of Beta-Blocker Effect.
Article in Journal of current ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
Purpose: To compare the effects of topical treatments with and without beta-blockers on diurnal and nocturnal intraocular pressure (IOP), systemic blood pressure (BP), and ocular perfusion pressure (OPP) in patients with normal-tension glaucoma (NTG). Methods: NTG patients followed at the Glaucoma Unit of the Department of Ophthalmology, Sakarya University Training and Research Hospital between 2020 and 2025 were retrospectively analyzed. Patients receiving beta-blocker-containing therapy (Group 2, Results: Patients using beta-blockers had significantly lower diurnal and nocturnal systolic BP (SBP) compared to the nonbeta-blocker group (P Conclusions: In NTG patients, beta-blocker use reduces diurnal SBP and diurnal OPP but has no significant effect on 24-h IOP or nocturnal OPP. These findings support the critical role of systemic hemodynamics and ocular perfusion in NTG progression and suggest that beta-blockers should be monitored carefully for OPP effects, especially in normotensive patients.
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