ArticleBioelectricity2026
A Wide-Band Coplanar Waveguide Delivery System for Sub-Nanosecond Pulsed Electric Fields Exposure.
Article in Bioelectricity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
Sub-nanosecond pulsed electric fields (sub-nsPEFs) present a promising tool for cellular and intracellular electro-manipulation. In this article, we propose a microfluidic device based on a coplanar waveguide (CPW) for high-intensity sub-nsPEF delivery and biomedical investigations. To deliver high-intensity and ultra-short-duration pulses, the CPW device features a miniaturized gap width of 345 µm. Numerical simulations and measurements confirm that this device presents a return loss lower than -10 dB over a wide frequency bandwidth, up to 3.7 GHz. Additionally, the results demonstrate a consistent electric field homogeneity within the CPW channels, particularly in the central area where the biological samples will be exposed. The CPW-based device was characterized under high-voltage sub-nanosecond duration pulse exposure. The results evidenced that the device is suitable for the delivery of ∼18 MV/m intensity and 500 ps duration pulses.
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