ArticleJournal of neurological surgery. Part B, Skull base2026
Postoperative CSF Characteristics After Extended Endoscopic Skull Base Surgery: Case Series and Review of the Literature.
Article in Journal of neurological surgery. Part B, Skull base, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Extended endoscopic endonasal approaches (EEA) to the skull base are associated with a greater risk of CSF leak and infection than standard trans-sellar cases. Postoperative CSF characteristics such as intracranial pressure, cytology, and microbiology are closely associated with this risk but have not previously been described. Study Design: Consecutive patients undergoing extended EEA at our tertiary center underwent lumbar puncture 3 to 5 days after surgery in accordance with local protocol. Opening pressure (OP) and CSF characteristics were obtained from the medical record and reported descriptively. The incidence of CSF leak, meningitis, and any predictive factors of these complications were then evaluated. Results: A total of 43 patients met inclusion criteria, of which 36 were female (83.7%) and 24 (55.8%) underwent EEA for anterior fossa meningioma. Out of 43 patients, 28 (65.1%) had a recorded OP (median 16 cmH Conclusion: The risk of CSF leak and meningitis in a modern cohort of patients undergoing extended EEA is low. However, 32.1% of patients in this cohort had an elevated opening pressure and 4.7% had unexpected CSF pleocytosis. Careful consideration of these factors and their possible impact on postoperative morbidity is essential.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.