ArticleFrontiers in neurology
Global landscape of registered clinical trials of stem cell therapy for spinal cord injury: a cross-sectional analysis.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stem cell therapy is a promising regenerative strategy for spinal cord injury (SCI), but its clinical development remains heterogeneous. This study analyzed the global landscape of registered interventional trials to characterize current translational progress. We performed a cross-sectional analysis of interventional clinical trials of stem cell therapy for SCI using the Informa Trialtrove database. Records available through December 31, 2025 were screened. Observational studies, duplicate registrations, and studies not directly evaluating stem cell-based treatment for SCI were excluded. Data on trial year, country, phase, status, sponsor, cell type, and primary endpoints were extracted. Eighty interventional trials were included. Trial activity increased overall from 2008 onward, with continued study initiation in 2024 and 2025. China contributed the largest number of trials (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.