ArticleFrontiers in neurology
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Intrasaccular devices such as SEAL™ and WEB™-SL are designed to disrupt aneurysmal flow. We present a new Methods: Particle image velocimetry (PIV) method was used in a patient-specific middle cerebral artery (MCA) wide-neck bifurcation aneurysm (WNBA) model to measure velocity, residence time (RT), and vorticity strength (VS). Tested devices included 3 each of SEAL-BASE (6 × 2 mm), SEAL-ARC (6 × 5 mm), and WEB-SL (6 × 4 mm). Results: Twelve experiments were performed (3 unique devices per size and 3 controls); the mean RT was 0.042 ± 0.006 s (control) and increased with SEAL-BASE (0.387 ± 0.128), SEAL-ARC (0.33 ± 0.092), and WEB-SL (0.171 ± 0.034) (all Conclusion: Both SEAL configurations achieved greater flow reduction compared to the WEB-SL of similar width in the same aneurysm model. Results highlight the unique utilization of the PIV method for the mechanistic decoupling of momentum transfer into the aneurysm sac resulting from intra-aneurysmal mesh structures and point toward their potential for further neurointerventional device optimization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.