Trial reportFrontiers in neurology
Electroacupuncture improves upper-limb motor function and modulates sensorimotor network connectivity in subacute stroke: a randomized controlled trial.
Trial report in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Electroacupuncture (EA) has been shown to facilitate post-stroke motor recovery; however, the underlying neurophysiological mechanisms remain insufficiently understood. This study aimed to investigate how EA modulates sensorimotor network (SMN) connectivity and to explore its relationship with upper-limb motor recovery in patients with subacute stroke. Methods: Fifty patients with subacute stroke were randomly assigned to the EA group or sham EA (SEA) group. All participants received 18 treatment sessions over 3 weeks in addition to standard rehabilitation. Upper-limb motor function and daily living ability were assessed before and after treatment. Resting-state electroencephalography (EEG) was recorded before and after the intervention. Functional connectivity (FC) within the SMN was calculated using phase-locking value (PLV) in the alpha (8-13 Hz) and beta (13-30 Hz) bands. Graph-theoretical metrics were analyzed, and partial least squares regression (PLSR) was used to evaluate associations between FC alterations and motor improvement. Results: After treatment, the EA group showed significantly greater improvement in upper-limb motor function than the SEA group, as indicated by a significant group × time interaction for the Fugl-Meyer Assessment for Upper Extremity (FMA-UE) and greater between-group gains in change scores ( Conclusion: EA improved upper-limb motor recovery in patients with subacute stroke and was accompanied by selective enhancement of alpha-band functional connectivity within the sensorimotor network. These findings suggest that EA may promote post-stroke motor recovery through frequency-specific reorganization of recovery-relevant sensorimotor circuits. Clinical trial registration: https://www.chictr.org.cn/bin/project/edit?pid=199590, Chinese Clinical Trial Registry (Registration number: ChiCTR2300077420).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.