Evidence map›Paper›PMID 42403916›Full record

ArticleInternational journal of pediatrics2026

Infant Dyschezia Is Associated With Increased Risk of Functional Constipation in Childhood: A Case-Control Study.

Mahbod Kaveh, Arman Malekiantaghi, Hamideh Mohammadi, Hosein Shabani-Mirzaee, Kambiz Eftekhari

Abstract read
In one paragraph

Article in International journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mahbod KavehDepartment of Neonatology, Bahrami Children's Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran, tums.ac.ir.ORCID https://orcid.org/0000-0001-6973-8845
Arman MalekiantaghiDepartment of Pediatric Gastroenterology, Bahrami Children's Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran, tums.ac.ir.ORCID https://orcid.org/0000-0002-0110-9580
Hamideh MohammadiDepartment of Pediatric, Bahrami Children's Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran, tums.ac.ir.ORCID https://orcid.org/0009-0004-5961-5349
Hosein Shabani-MirzaeeDepartment of Pediatric, Bahrami Children's Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran, tums.ac.ir.ORCID https://orcid.org/0000-0002-6051-7509
Kambiz EftekhariPediatric Gastroenterology and Hepatology Research Center, Department of Pediatric Gastroenterology, Bahrami Children's Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran, tums.ac.ir.ORCID https://orcid.org/0000-0003-3471-2498

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Functional constipation (FC) frequently occurs in children and leads to notable discomfort as well as substantial healthcare costs. Infant dyschezia (ID) is characterized by excessive straining and crying before passing soft stools in infants and is traditionally considered benign and self-limiting. However, emerging evidence suggests a possible link between ID and later chronic bowel dysfunction. The objective of this work was to examine whether a history of ID is linked to the later emergence of FC during childhood. Methods: We recruited 150 children for this case-control investigation, including 90 individuals diagnosed with FC and 60 healthy controls, all from a tertiary pediatric outpatient clinic. Diagnoses were based on Rome IV criteria. Data on demographics, infant feeding, family history of constipation, and history of ID were collected through structured interviews. We applied logistic regression analysis to determine which factors independently predicted FC. Results: Children with FC were significantly more likely than controls to have a history of ID (66.7% vs. 40.0%, Conclusion: These results indicate that ID could serve as an independent risk factor for childhood FC. Early recognition and parental guidance are essential to prevent mismanagement and long-term morbidity. Longitudinal studies are recommended to confirm causality and inform preventive strategies.

Indexed as

functional constipationinfant dyscheziapediatric gastrointestinal disordersRome IV criteria

Identifiers

PMID42403916
PMCPMC13329262

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.