ReviewOpen forum infectious diseases2026
Impact of Multiplex PCR Blood-Culture Identification Panels on Clinical Outcomes, Antimicrobial Stewardship, and Economic Impact in US Hospitals: A Systematic Review and Meta-Analysis.
Review in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: We performed a systematic review and meta-analysis synthesizing evidence on multiplex PCR blood culture identification (BCID) panels and their effects on clinical, antimicrobial stewardship, and economic outcomes. Methods: We searched PubMed, Scopus, Embase, CINAHL, Web of Science, and the Cochrane Library for studies evaluating time to appropriate therapy, mortality, length of stay (LOS), antimicrobial optimization, and cost in adult inpatients. Results: Twenty studies encompassing 4587 patients with bloodstream infections across U.S. hospitals were included. BCID implementation showed shorter time to appropriate antimicrobial therapy by 17.28 hours (95% CI, -24.00 to -10.56) and hospital LOS by 1.25 days (95% CI, -1.79 to -.71). No statistically significant effect on mortality was observed (OR, 1.04; 95% CI, .81-1.34). Economic outcomes were not significantly different. Conclusions: BCID panels were associated with shorter time to effective therapy; however, a timely clinical response is necessary.
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