Evidence map›Paper›PMID 42403896›Full record

ArticleFrontiers in cardiovascular medicine2026

Associations of the TyG index, remnant cholesterol levels, and the severity of coronary artery disease: findings from a retrospective study.

Xi Meng, Yibo Duanmu, Xiaoyi Yu, Lijie Liu, Yuhui Cui, Zhimin Chen, Guiyuan Ji, Dantao Zhang, Xingfen Yang, Xilong Liu and 1 more

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Xi Meng *Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
Yibo Duanmu *Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Xiaoyi YuDepartment of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Lijie LiuDepartment of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yuhui CuiDepartment of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Zhimin ChenDepartment of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Guiyuan JiGuangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
Dantao ZhangGuangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
Xingfen YangNMPA Key Laboratory for Safety Evaluation of Cosmetics, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China.
Xilong LiuDepartment of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Wei WuGuangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to investigate whether the triglyceride-glucose (TyG) index mediates the association between remnant cholesterol (RC) and coronary artery disease (CAD) severity and to evaluate their combined association with multi-vessel CAD. Methods: In this retrospective study, anonymized data from CAD patients undergoing coronary computed tomography angiography (CCTA) or coronary angiography (CAG) between 2019 and 2022 were analyzed Results: A total of 592 patients (64.7% male; mean age, 62 years) were included in the analysis. The TyG index was positively correlated with RC ( Conclusions: The TyG index is positively correlated with RC and is significantly associated with CAD severity. Furthermore, the TyG index partially mediates the association between RC and CAD severity. Combined assessment of the TyG index and RC may improve metabolic risk stratification in patients with CAD.

Indexed as

insulin resistancemediation analysisremnant cholesterolseverity of coronary artery diseasetriglyceride-glucose index

Identifiers

PMID42403896
PMCPMC13328199

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