ArticleCureus2026
Rare, Locally Advanced Presentation of Giant Scalp Squamous Cell Carcinoma: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Giant cutaneous squamous cell carcinoma (cSCC) of the scalp is rare and presents significant therapeutic challenges due to its size, proximity to critical neurovascular structures, and complex reconstructive requirements. We report a 68-year-old woman with a 20 cm exophytic occipito-parietal cSCC that had been evolving over one year. Biopsy confirmed a well-differentiated cSCC, and imaging revealed a heterogeneous mass abutting the skull without nodal or distant metastases. The tumor was managed with wide surgical excision, including the cranial periosteum and outer table curettage, followed by staged reconstruction using pedicled transposition flaps and split-thickness skin grafts. Histopathology confirmed a well-differentiated infiltrative cSCC (T3N0M0, American Joint Committee on Cancer (AJCC) stage III) with clear margins. Postoperative outcomes were satisfactory, both functionally and aesthetically. This case underscores the importance of early detection, multidisciplinary management, and individualized surgical planning in giant scalp cSCC, with adjuvant therapies offering additional options for advanced disease.
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