ArticleCureus2026
Radiological and Histopathological Correlative Analysis of Bone Tumors and Tumor-Like Lesions at a Tertiary Care Center.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBone tumors and tumor-like lesions represent a heterogeneous group of disorders with overlapping clinical and radiological characteristics, often posing diagnostic challenges in routine practice. The present study aimed to evaluate the spectrum of bone tumors and tumor-like lesions encountered at a tertiary care hospital in eastern India and to assess the concordance between radiological and histopathological diagnoses. MATERIALS AND
methodsThis prospective observational study was conducted in the Department of Pathology over 18 months and included 125 patients with clinically and radiologically suspected bone lesions who underwent biopsy or surgical intervention. Radiological findings were correlated with histopathological examination, and concordance was assessed using Cohen's kappa statistic. A p-value <0.05 was considered significant.
resultsMost patients were below 30 years of age (98, 78%), with male predominance (72, 58%). Swelling associated with pain (48, 38%) was the most common presenting symptom, and the femur was the most frequently involved bone. Radiological evaluation categorized 52 (42%) lesions as malignant, whereas histopathology identified malignancy in 47 (38%) cases. Osteosarcoma was the most common malignant tumor. Overall concordance between radiological and histopathological diagnoses was observed in 106 (85%) cases, with a kappa value of 0.636 indicating statistically significant moderate agreement.
conclusionsRadiological evaluation demonstrated moderate agreement with histopathological diagnosis and served as an effective preliminary diagnostic modality in bone tumors and tumor-like lesions. However, histopathological examination remained essential for a definitive diagnosis because of overlapping imaging features among benign, aggressive, and malignant lesions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.