Evidence map›Paper›PMID 42403734›Full record

ArticleCureus2026

Boerhaave Syndrome With Concomitant Duodenal Perforation: A Rare Case Complicated by Mediastinitis and Empyema.

Fotini Ampatzidou, Maria Papaioannou, Athanasios Xakis, Anastasia Argyropoulou, Athina Lavrentieva

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fotini Ampatzidou1st Intensive Care Unit, General Hospital of Thessaloniki "G. Papanikolaou", Thessaloniki, GRC.
Maria Papaioannou1st Intensive Care Unit, General Hospital of Thessaloniki "G. Papanikolaou", Thessaloniki, GRC.
Athanasios Xakis2nd Surgery Department, General Hospital of Thessaloniki "G. Papanikolaou", Thessaloniki, GRC.
Anastasia Argyropoulou1st Intensive Care Unit, General Hospital of Thessaloniki "G. Papanikolaou", Thessaloniki, GRC.
Athina Lavrentieva1st Intensive Care Unit, General Hospital of Thessaloniki "G. Papanikolaou", Thessaloniki, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Boerhaave syndrome (spontaneous esophageal rupture) remains a surgical emergency with high mortality, particularly when complicated by mediastinitis, pleural empyema, and septic shock. Concomitant intra-abdominal perforation significantly increases morbidity. We report a case of a 61-year-old male patient presenting with hemodynamic instability due to distal esophageal rupture and duodenal perforation. Imaging revealed bilateral pneumothorax, pneumomediastinum, pneumoperitoneum, and extensive pleural effusions. The patient underwent emergent exploratory laparotomy with esophageal repair over T-tube placement, mediastinal lavage, primary duodenal repair, bilateral chest tube placement, decompressive gastrostomy, and feeding jejunostomy. The postoperative course was complicated by septic shock, bilateral pleural empyema requiring re-interventions including thoracotomy and pleurodesis, multidrug-resistant pulmonary infections, axillary vein thrombosis,

Indexed as

boerhaave syndromecritical careduodenal perforationempyemaesophageal ruptureseptic shockthoracotomy

Identifiers

PMID42403734
PMCPMC13332180

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.