Primary Ewing sarcoma of the pancreas: A rare extraosseous presentation.

Elias Lugo-Fagundo, Connor W Smith, Felipe Lopez-Ramirez, Elliot K Fishman

Abstract readCase Reports

In one paragraph

Article in Radiology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Elias Lugo-FagundoRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 601 N Caroline St, Baltimore, MD 21287, USA.

Connor W SmithRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 601 N Caroline St, Baltimore, MD 21287, USA.

Felipe Lopez-RamirezRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 601 N Caroline St, Baltimore, MD 21287, USA.

Elliot K FishmanRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 601 N Caroline St, Baltimore, MD 21287, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ewing sarcoma is an aggressive neoplasm that is common among children and adolescents, most frequently affecting the pelvis and long bones. Although rare, Ewing sarcoma is known to also occur in extraosseous locations, affecting a broad range of soft tissue structures. The diagnosis of extraosseous Ewing sarcoma is difficult given the nonspecific symptomatology, often related to local tumor burden. Radiological features of this entity overlap with other common malignancies, as Ewing sarcoma typically presents on computed tomography (CT) as a heterogeneous mass containing areas of necrosis and calcification. Imaging plays a central role in the evaluation of this entity, but histologic and molecular analysis remain necessary for definitive diagnosis. We report the case of a 40-year-old female with a primary pancreatic extraosseous Ewing sarcoma. We correlate clinical indicators with imaging findings and pathological analysis to discuss this patient's long-term outcome following multimodal therapy.

Indexed as

Computed tomographyEwing sarcomaPancreas

Identifiers

PMID42403662

DOI10.1016/j.radcr.2026.05.069

PMCPMC13330597

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