Evidence map›Paper›PMID 42403563›Full record

ArticleProceedings. IEEE International Conference on Computer Vision2023

CLIP-Driven Universal Model for Organ Segmentation and Tumor Detection.

Jie Liu, Yixiao Zhang, Jie-Neng Chen, Junfei Xiao, Yongyi Lu, Bennett A Landman, Yixuan Yuan, Alan Yuille, Yucheng Tang, Zongwei Zhou

Abstract read
In one paragraph

Article in Proceedings. IEEE International Conference on Computer Vision, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  6. Review
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  8. Review
  9. OpenVocabCT: Toward Universal Text-Driven CT Image Segmentation.IEEE transactions on medical imaging · 2026
    Article
  10. LEARNABLE HIERARCHICAL VISUAL CONTEXTS FOR TUMOR SEGMENTATION IN COMPUTED TOMOGRAPHY IMAGES.Proceedings. IEEE International Symposium on Biomedical Imaging · 2026
    Article
  11. Article
  12. Article
  13. Foundation Models Meet Medical Image Interpretation.Research (Washington, D.C.) · 2026
    Review
  14. Article
  15. Article
  16. Backdoor in Seconds: Unlocking Vulnerabilities in Large Pre-trained Models via Model Editing.Proceedings of the ... ACM International Conference on Information & Knowledge Management. ACM International Conference on Information and Knowledge Management · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jie LiuCity University of Hong Kong.
Yixiao ZhangJohns Hopkins University.
Jie-Neng ChenJohns Hopkins University.
Junfei XiaoJohns Hopkins University.
Yongyi LuJohns Hopkins University.
Bennett A LandmanVanderbilt University.
Yixuan YuanChinese University of Hong Kong.
Alan YuilleJohns Hopkins University.
Yucheng TangVanderbilt University.
Zongwei ZhouJohns Hopkins University.

Funding

Automated Multi-Timepoint CT Analysis for Enhanced Metastatic Disease Evaluation in Colorectal Cancer: An Anatomy-Aware Vision-Language AI ApproachR01EB037669 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Kang Wang, Yang Yang · 2025 to 2026
$1.4M
NIBIB NIH HHS R01 EB037669
6 · The paper itself

Abstract

An increasing number of public datasets have shown a marked impact on automated organ segmentation and tumor detection. However, due to the small size and partially labeled problem of each dataset, as well as a limited investigation of diverse types of tumors, the resulting models are often limited to segmenting specific organs/tumors and ignore the semantics of anatomical structures, nor can they be extended to novel domains. To address these issues, we propose the CLIP-Driven Universal Model, which incorporates text embedding learned from Contrastive Language-Image Pre-training (CLIP) to segmentation models. This CLIP-based label encoding captures anatomical relationships, enabling the model to learn a structured feature embedding and segment 25 organs and 6 types of tumors. The proposed model is developed from an assembly of 14 datasets, using a total of 3,410 CT scans for training and then evaluated on 6,162 external CT scans from 3 additional datasets. We rank first on the Medical Segmentation Decathlon (MSD) public leaderboard and achieve state-of-the-art results on Beyond The Cranial Vault (BTCV). Additionally, the Universal Model is computationally more efficient (6× faster) compared with dataset-specific models, generalized better to CT scans from varying sites, and shows stronger transfer learning performance on novel tasks.

Identifiers

PMID42403563
PMCPMC13332747

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.