Evidence map›Paper›PMID 42403239›Full record

ReviewGlobal spine journal2026

Clinical Outcomes Following Three- and Four-Level Anterior Cervical Discectomy and Fusion: A Systematic Review and Meta-Analysis.

Tyler M Compton, Ravi A Patel, Mark A Plantz, Rohan M Shah, Theodore A Joaquin, Jacob R Staub, Daniel E Herrera, Cade F Bennett, Anitesh Bajaj, Abhinav R Balu and 4 more

Abstract readReview
In one paragraph

Review in Global spine journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tyler M ComptonDepartment of Orthopaedic Surgery, Northwestern Memorial Hospital, Chicago, IL, USA.
Ravi A PatelDepartment of Orthopaedic Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Mark A PlantzDepartment of Orthopaedic Surgery, Northwestern Memorial Hospital, Chicago, IL, USA.
Rohan M ShahDepartment of Orthopaedic Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Theodore A JoaquinDepartment of Orthopaedic Surgery, Northwestern Memorial Hospital, Chicago, IL, USA.ORCID 0009-0002-2474-7857
Jacob R StaubDepartment of Surgery, Temple University Hospital, Philadelphia, PA, USA.ORCID 0009-0007-2576-1446
Daniel E HerreraDepartment of Orthopaedic Surgery, Medical College of Georgia, Augusta, GA, USA.ORCID 0009-0009-3487-3073
Cade F BennettDepartment of Orthopaedic Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Anitesh BajajDepartment of Orthopaedic Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Abhinav R BaluDepartment of Orthopaedic Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Matthew W ColmanDepartment of Orthopaedic Surgery, Northwestern Memorial Hospital, Chicago, IL, USA.
Wellington K HsuDepartment of Orthopaedic Surgery, Northwestern Memorial Hospital, Chicago, IL, USA.
Alpesh A PatelDepartment of Orthopaedic Surgery, Northwestern Memorial Hospital, Chicago, IL, USA.
Srikanth N DiviDepartment of Orthopaedic Surgery, Northwestern Memorial Hospital, Chicago, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Study Design/SettingSystematic review and meta-analysis.ObjectivesAnterior cervical discectomy and fusion (ACDF) is a well-established treatment for degenerative cervical pathology. Although outcomes following 1- and 2-level ACDF are favorable, increasing construct length has been associated with worse outcomes. Despite this, 3- and 4-level ACDF are often grouped as "multilevel" constructs, though emerging evidence suggests 4-level ACDF may carry greater risk. This study systematically reviewed the literature and performed a meta-analysis comparing outcomes between 3- and 4-level ACDF.MethodsA systematic search of MEDLINE, Embase, and Cochrane databases was performed per PRISMA guidelines. Studies reporting outcomes following three- or four-level ACDF were included.

Indexed as

anterior cervical discectomy and fusionclinical outcomesmeta-analysissystematic review

Identifiers

PMID42403239
PMCPMC13337568

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.