Observational studyThe Journal of international medical research2026
Association of an integrated prehospital-to-in-hospital transfusion workflow with early outcomes in severe trauma requiring emergency transfusion: A single-center observational before-and-after study.
Observational study in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
ObjectiveTo evaluate the association between a prehospital-to-in-hospital integrated transfusion workflow and transfusion timeliness, coagulation-related indices, and short-term clinical outcomes in patients with severe trauma requiring emergency transfusion.MethodsThis single-center observational before-and-after study included 120 consecutive patients with severe trauma requiring emergency transfusion (60 per group). The conventional workflow group included patients treated between January 2022 and August 2023, and the integrated workflow group included patients treated between January 2024 and March 2025. The integrated workflow comprised prehospital assessment, real-time pre-arrival communication, early activation of emergency and transfusion resources, electronic transfusion ordering, and dedicated blood product delivery. The primary outcome was time to first transfusion, interpreted as a process-efficiency measure. Secondary outcomes included coagulation-related indices before transfusion and at 24 h, 24-h blood product utilization, intensive care unit length of stay, and in-hospital mortality. Univariable and multivariable analyses were performed to evaluate the association between workflow group and key outcomes.ResultsBaseline demographic, clinical, and pretransfusion laboratory characteristics were generally comparable between groups. The integrated workflow group had a shorter time to first transfusion than the conventional workflow group (25.1 ± 6.4 vs. 56.3 ± 8.2 min,
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