Evidence map›Paper›PMID 42402900›Full record

ArticleMagnetic resonance in medicine2026

Feasibility and SNR Performance of Hyperpolarized

Agilo L Kern, Marcel Gutberlet, Jens M Hohlfeld, Frank Wacker, Jens Vogel-Claussen

Abstract read
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In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Agilo L KernInstitute for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0003-4157-9808
Marcel GutberletInstitute for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Jens M HohlfeldBiomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.
Frank WackerInstitute for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Jens Vogel-ClaussenInstitute for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.

Funding

German Center for Lung Research (DZL)
6 · The paper itself

Abstract

purposeTo develop a balanced SSFP (bSSFP) sequence for pulmonary

methods12 healthy volunteers underwent hyperpolarized

resultsNormalized SNR of the first echo was significantly greater for bSSFP compared to FLASH with the same flip angle, p = 0.003, but not with lower flip angle resulting in equivalent depolarization, p = 0.98. The effective number of signal averages in signal decomposition was significantly higher compared to FLASH with both flip angles and both dissolved resonances, p < 0.008. Neglecting the finite readout duration was found to introduce bias of derived RBC-M ratios but prevent noise amplification.

conclusionHyperpolarized

Indexed as

Image Processing, Computer-AssistedLungMagnetic Resonance ImagingXenon IsotopesAdultAlgorithmsFeasibility StudiesFemaleHealthy VolunteersHumansMalePulmonary Gas ExchangeReproducibility of ResultsSignal Processing, Computer-AssistedSignal-To-Noise Ratiohyperpolarized Xe-129Xenon Isotopes129XebSSFPdissolved phasegas exchangehyperpolarizationlung

Identifiers

PMID42402900
PMCPMC13527243

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.