Evidence map›Paper›PMID 42402581›Full record

Observational studyCardiovascular ultrasound2026

Computer modeling to improve measurement of stroke volume with echocardiography.

Sarah Balderston Murthi, Shiming Yang, Peter P Oliveri, Sami Safadi, Sydea Fatima, William Teeter

Abstract readObservational Study
In one paragraph

Observational study in Cardiovascular ultrasound, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sarah Balderston MurthiSchool of Medicine, University of Maryland, Baltimore, USA. smurthi@som.umaryland.edu.
Shiming YangSchool of Medicine, University of Maryland, Baltimore, USA.
Peter P OliveriSchool of Medicine, University of Maryland, Baltimore, USA.
Sami SafadiDepartments of Nephrology and Pulmonary Critical Care , University of Minnesota, Minneapolis, USA.
Sydea FatimaSchool of Medicine, University of Maryland, Baltimore, USA.
William TeeterSchool of Medicine, University of Maryland, Baltimore, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe stroke volume (SV) can be measured by a human expert (HE) using the left ventricular outflow tract diameter (LVOTd) and its velocity time integral (VTI) with echo. If the SV is known, the cardiac output and systemic vascular resistance can be calculated. We have previously described a machine learning computer model (CM) to estimate the LVOTd. The accuracy of LVOTd

methodOver 20 months, a prospective observational study was done in patients with a PAC placed for clinical indications. Participants underwent an echocardiogram, and at the same time the SV was measured by PAC. The SV with echo was calculated using the LVOTd

resultsComputer modeling improves measurement of stroke volume with echocardiography. Eighty-four patients with a PAC were enrolled. With human expert measurement of the LVOTd and the VTI, the SV could be calculated in 59 (70%), and with the LVOTd

conclusionsA machine learning model of the LVOTd allows accurate calculation of the SV using only the VTI, simplifying the assessment while increasing the yield by 22%. Machine learning tools can lower the bar for obtaining quantitative metrics with echo. Adding objective and repeatable measures will improve the ability of echo to guide therapy in the critically ill.

Indexed as

Computer SimulationEchocardiographyHeart VentriclesImage Interpretation, Computer-AssistedMachine LearningStroke VolumeAgedFemaleHumansMaleMiddle AgedProspective StudiesReproducibility of Results

Identifiers

PMID42402581
PMCPMC13335344

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.