ReviewEJNMMI reports2026
PET/CT contouring techniques in neuroendocrine neoplasms: a state-of-the-art scoping review.
Review in EJNMMI reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNeuroendocrine neoplasms (NENs) are often metastatic at diagnosis and show great variation in primary site and biological behaviour. Although PET is often used to image NENs, contouring is challenging because NEN lesions are heterogenous. This scoping review examines the literature on NEN contouring in clinical settings.
methodsThe scoping review follows the PRISMA-ScR guidelines. Published studies between 2010 and 2025 and conference abstracts and proceedings between 2023 and 2025 were included. Eligible studies included studies with at least 5 patients with NEN, involved PET imaging analysis with the measurement of at least one quantitative variable, and used a thresholding method to determine lesion contours.
resultsThirty-seven articles and 17 conference abstracts were included in the review. Sixteen articles investigated flat contouring methods, 11 investigated relative contouring approaches, 3 investigated both, 6 used manual contouring exclusively, and 1 did not explicitly describe the contouring method. Twenty-five articles used radiopharmaceuticals targeting somatostatin receptors (SSTR) only, 5 used [
conclusionsFlat contouring methods were most commonly used for the contouring of NENs and are clinically applicable. Therefore, investigating the prognostic value of quantitative parameters derived from flat contouring methods could yield an optimised NEN lesion contouring methodology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.