Evidence map›Paper›PMID 42402491›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2026

Long-term functional outcomes following pediatric decompressive craniectomy for traumatic brain injury.

Julian Michael Burwell, Brandon Gonzalez, Blandine Ehinnou, Lara Nasser, Jessica Huang, Clemens Maria Schirmer

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Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Julian Michael BurwellDepartment of Medical Education, Geisinger Commonwealth School of Medicine, Scranton, PA, USA.ORCID 0009-0006-1059-5134
Brandon GonzalezDepartment of Medical Education, Geisinger Commonwealth School of Medicine, Scranton, PA, USA.ORCID 0009-0004-2324-3416
Blandine EhinnouDepartment of Medical Education, Geisinger Commonwealth School of Medicine, Scranton, PA, USA.ORCID 0009-0001-6034-1769
Lara NasserDepartment of Medical Education, Geisinger Commonwealth School of Medicine, Scranton, PA, USA.ORCID 0009-0002-3579-1976
Jessica HuangDepartment of Medical Education, Geisinger Commonwealth School of Medicine, Scranton, PA, USA.ORCID 0000-0002-8971-2180
Clemens Maria SchirmerDepartment of Neurosurgery, Geisinger Health Systems, Wilkes-Barre, PA, USA. cmschirmer@gmail.com.ORCID 0000-0003-1743-8781

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDetermine whether there is a difference in 5-year functional outcomes between pediatric head trauma cases who received DC vs. non-operative management (NOM).

methodsA seven-year (2017-2024) retrospective, case-control study of 195 pediatric trauma admissions (ages 2-18) at two Level-1 Trauma Centers. Subjects with primary head trauma and GCS ≤ 12 were included. Cases were divided into two matched cohorts based on age, sex, and injury severity. The DC group was characterized by surgical indication, and non-operative management (NOM) interventions were recorded by tier per Brain Trauma Foundation guidelines. Outcomes were assessed annually over five years using GOSE and KOSCHI. Statistical tests included χ

resultsTwenty-six matched pairs (n = 52) were included in the final analysis. The DC group had markedly worse intracranial pathology, including midline shift (38.46% DC vs 0% NOM, p = .001) and cisternal compression (65.38% DC vs 7.69% NOM, p < .001), along with higher hospital mortality (15.38% DC vs 0% NOM). CMH shift testing of GOSE and KOSCHI demonstrated comparable outcomes between cohorts from years one through four (p = .068). At five years, the NOM group exhibited a trend toward better outcomes (p = .046), although interpretation was limited by a small sample size at this time point (n = 5), with the remainder lost to follow-up. Notably, no DC survivors with available follow-up data demonstrated functional decline over time. On follow-up, neurological symptoms sequelae were more common in the DC group, while psychiatric complaints were more frequently reported in the NOM group.

conclusionDespite significantly worse intracranial pathology, DC patients who remained in follow-up achieved comparable functional outcomes to NOM patients through four years.

Indexed as

Brain Injuries, TraumaticDecompressive CraniectomyRecovery of FunctionAdolescentCase-Control StudiesChildChild, PreschoolFemaleHumansMaleRetrospective StudiesTreatment OutcomeDecompressive CraniectomyFunctional OutcomesOutcomes ResearchPediatric NeurosurgeryTraumatic Brain Injury

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.