ArticlePharmacoepidemiology and drug safety2026
A Drug-Environment Interaction Between PM
Article in Pharmacoepidemiology and drug safety, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
11 authors.
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Abstract
backgroundFew studies have investigated the interaction between drug-environment despite the plausibility and concern. We sought to explore the synergistic effects of corticosteroids and PM
objectivesTo assess the synergistic effect of corticosteroid use and PM
methodsWe conducted a retrospective cohort study using the Taiwan National Health Insurance database from 2009 to 2019. We included patients aged 65 years or older and at high risk for cardiovascular and thromboembolic events. Exposures included corticosteroid therapy and seasonal mean PM
resultsThe cohort included 373 402 participants, with average age at index date 73.6 ± 7.2 years; 57.7% of cohort members were female. During the study period, 1 614 331 (43.2%) participants had at least one corticosteroid prescription. The average PM
conclusionsA synergistic effect between seasonal PM
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